The role of chromoendoscopy in the surveillance of the duodenum of patients with familial adenomatous polyposis

Massimo Picasso, Rosangela Filiberti, Sabrina Blanchi, Massimo Conio

Research output: Contribution to journalArticle

Abstract

Adenomas of the duodenum have been described in patients with familial adenomatous polyposis (FAP). Patients with FAP are at high risk for the development of periampullary cancer. The aim of our study was to evaluate if endoscopic visualization of small polyps, often overlooked at standard endoscopic examination, was improved by chromoendoscopy. Ten patients with FAP and previous colectomy underwent upper gastrointestinal endoscopy. Two skilled endoscopists were involved for each endoscopy. Evaluation of number and diameter of polyps was made before and after staining. After staining we detected a larger number of duodenal polyps than found at the standard endoscopic examination, the difference being statistically significant. This result seems to suggest that chromoendoscopy may improve diagnostic yield of endoscopy. Further studies are needed to suggest the best surveillance program and the appropriate therapeutic modality for these patients.

Original languageEnglish
Pages (from-to)1906-1909
Number of pages4
JournalDigestive Diseases and Sciences
Volume52
Issue number8
DOIs
Publication statusPublished - Aug 2007

Keywords

  • Chromoendoscopy
  • Familial adenomatous polyposis
  • Surveillance

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'The role of chromoendoscopy in the surveillance of the duodenum of patients with familial adenomatous polyposis'. Together they form a unique fingerprint.

  • Cite this