TY - JOUR
T1 - The Role of CT-scan Studies for the Diagnosis and Therapy of Acute Respiratory Distress Syndrome
AU - Gattinoni, Luciano
AU - Caironi, Pietro
AU - Valenza, Franco
AU - Carlesso, Eleonora
PY - 2006/12
Y1 - 2006/12
N2 - The authors have investigated ARDS using CT scanning for more than 20 years. The unique ability of CT scanning to provide a quantitative approach to observing the lung parenchyma has made it possible to understand better the pathophysiology of ARDS. The authors believe that today CT scanning, in addition to its use in research, may be an essential tool allowing a rational setting of mechanical ventilation in patients who have ARDS. The assessment of lung recruitability should guide a correct setting of PEEP. Moreover, the quantification of the portion of the lung open to ventilation should lead to the application of a safe tidal volume, without excessive alveolar strain. Future studies will investigate the efficacy of these approaches on outcome.
AB - The authors have investigated ARDS using CT scanning for more than 20 years. The unique ability of CT scanning to provide a quantitative approach to observing the lung parenchyma has made it possible to understand better the pathophysiology of ARDS. The authors believe that today CT scanning, in addition to its use in research, may be an essential tool allowing a rational setting of mechanical ventilation in patients who have ARDS. The assessment of lung recruitability should guide a correct setting of PEEP. Moreover, the quantification of the portion of the lung open to ventilation should lead to the application of a safe tidal volume, without excessive alveolar strain. Future studies will investigate the efficacy of these approaches on outcome.
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U2 - 10.1016/j.ccm.2006.06.002
DO - 10.1016/j.ccm.2006.06.002
M3 - Article
C2 - 17085245
AN - SCOPUS:33751068739
VL - 27
SP - 559
EP - 570
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
SN - 0272-5231
IS - 4
ER -