The Role of CT-scan Studies for the Diagnosis and Therapy of Acute Respiratory Distress Syndrome

Luciano Gattinoni; Pietro Caironi; Franco Valenza; Eleonora Carlesso

doi:10.1016/j.ccm.2006.06.002

The Role of CT-scan Studies for the Diagnosis and Therapy of Acute Respiratory Distress Syndrome

Luciano Gattinoni, Pietro Caironi, Franco Valenza, Eleonora Carlesso

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

The authors have investigated ARDS using CT scanning for more than 20 years. The unique ability of CT scanning to provide a quantitative approach to observing the lung parenchyma has made it possible to understand better the pathophysiology of ARDS. The authors believe that today CT scanning, in addition to its use in research, may be an essential tool allowing a rational setting of mechanical ventilation in patients who have ARDS. The assessment of lung recruitability should guide a correct setting of PEEP. Moreover, the quantification of the portion of the lung open to ventilation should lead to the application of a safe tidal volume, without excessive alveolar strain. Future studies will investigate the efficacy of these approaches on outcome.

Original language	English
Pages (from-to)	559-570
Number of pages	12
Journal	Clinics in Chest Medicine
Volume	27
Issue number	4
DOIs	https://doi.org/10.1016/j.ccm.2006.06.002
Publication status	Published - Dec 2006

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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abstract = "The authors have investigated ARDS using CT scanning for more than 20 years. The unique ability of CT scanning to provide a quantitative approach to observing the lung parenchyma has made it possible to understand better the pathophysiology of ARDS. The authors believe that today CT scanning, in addition to its use in research, may be an essential tool allowing a rational setting of mechanical ventilation in patients who have ARDS. The assessment of lung recruitability should guide a correct setting of PEEP. Moreover, the quantification of the portion of the lung open to ventilation should lead to the application of a safe tidal volume, without excessive alveolar strain. Future studies will investigate the efficacy of these approaches on outcome.",

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AB - The authors have investigated ARDS using CT scanning for more than 20 years. The unique ability of CT scanning to provide a quantitative approach to observing the lung parenchyma has made it possible to understand better the pathophysiology of ARDS. The authors believe that today CT scanning, in addition to its use in research, may be an essential tool allowing a rational setting of mechanical ventilation in patients who have ARDS. The assessment of lung recruitability should guide a correct setting of PEEP. Moreover, the quantification of the portion of the lung open to ventilation should lead to the application of a safe tidal volume, without excessive alveolar strain. Future studies will investigate the efficacy of these approaches on outcome.

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