Ruolo della deformabilità eritrocitaria sul prolungamento del tempo di emorragia nel paziente epatopatico.

Translated title of the contribution: The role of erythrocyte deformability in the prolonged bleeding time in liver disease patients

M. Moia, D. Mari, M. P. Coccato, P. Della Valle, A. Tripodi, P. M. Mannucci

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.

Original languageItalian
Pages (from-to)213-218
Number of pages6
JournalLa Ricerca in Clinica e in Laboratorio
Volume15 Suppl 1
Publication statusPublished - 1985

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Erythrocyte Deformability
Bleeding Time
Formability
Hematocrit
Liver
Liver Diseases
Chronic Disease
Platelets
Hemostasis
Platelet Count
Cells

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

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title = "Ruolo della deformabilit{\`a} eritrocitaria sul prolungamento del tempo di emorragia nel paziente epatopatico.",
abstract = "Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.",
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T1 - Ruolo della deformabilità eritrocitaria sul prolungamento del tempo di emorragia nel paziente epatopatico.

AU - Moia, M.

AU - Mari, D.

AU - Coccato, M. P.

AU - Della Valle, P.

AU - Tripodi, A.

AU - Mannucci, P. M.

PY - 1985

Y1 - 1985

N2 - Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.

AB - Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.

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