Abstract
Despite advances in antimicrobial therapy, community-acquired pneumonia (CAP) remains a common and potentially life-threatening infection. Fluoroquinolones appear to be a valid monotherapy alternative to the combination beta-lactam/macrolide therapy for non-severe hospitalised CAP, particularly in regions with a high prevalence of penicillin-resistant Streptococcus pneumoniae (PRSP) or in patients with a clinical risk of PRSP, and a key partner in the combination therapy given in casesof severe and intensive care unit-admitted CAP and when Pseudomonas aeruginosa infection is suspected. The high bioavailability of fluoroquinolones facilitates an early switch from intravenous to oral therapy.
Original language | English |
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Pages (from-to) | 61-65 |
Number of pages | 5 |
Journal | European Respiratory Disease |
Volume | 8 |
Issue number | 1 |
Publication status | Published - Mar 2012 |
Keywords
- Antibiotic resistance
- Community-acquired pneumonia
- Fluoroquinolones
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine