The role of glial cells in synaptic function

Alberto Bacci, Claudia Verderio, Elena Pravettoni, Michela Matteoli

Research output: Contribution to journalArticlepeer-review


Glial cells represent the most abundant cell population in the central nervous system and for years they have been thought to provide just structural and trophic support to neurons. Recently, several studies were performed, leading to the identification of an active interaction between glia and neurons. This paper focuses on the role played by glial cells at the level of the synapse, reviewing recent data defining how glia is determinant in synaptogenesis, in the modulation of fully working synaptic contacts and in synaptic plasticity.

Original languageEnglish
Pages (from-to)403-409
Number of pages7
JournalPhilosophical transactions of the Royal Society of London. Series B: Biological sciences
Issue number1381
Publication statusPublished - Feb 28 1999


  • Astrocytes
  • Glia - neuron interaction
  • Synaptic transmission
  • Synaptogenesis

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)


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