TY - JOUR
T1 - The role of hyaluronidase in the treatment of complications from hyaluronic acid dermal fillers
AU - Cavallini, Maurizio
AU - Gazzola, Riccardo
AU - Metalla, Marco
AU - Vaienti, Luca
PY - 2013/11
Y1 - 2013/11
N2 - Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Knowledge of the use, methods of application, and adverse effects of hyaluronidases is essential for the aesthetic practitioner. Therefore, we performed an extensive review of the available literature from 1928 to 2011 and compared the different enzymes available, recording each author's indications regarding usage and side effects.
AB - Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Knowledge of the use, methods of application, and adverse effects of hyaluronidases is essential for the aesthetic practitioner. Therefore, we performed an extensive review of the available literature from 1928 to 2011 and compared the different enzymes available, recording each author's indications regarding usage and side effects.
KW - cosmetic medicine
KW - dermal
KW - facial skin necrosis
KW - fillers
KW - hyaluronic acid
KW - hyaluronidase
KW - noninvasive plastic surgery
UR - http://www.scopus.com/inward/record.url?scp=84890541057&partnerID=8YFLogxK
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U2 - 10.1177/1090820X13511970
DO - 10.1177/1090820X13511970
M3 - Article
C2 - 24197934
AN - SCOPUS:84890541057
VL - 33
SP - 1167
EP - 1174
JO - Aesthetic Surgery Journal
JF - Aesthetic Surgery Journal
SN - 1090-820X
IS - 8
ER -