The role of imaging in juvenile idiopathic arthritis

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Introduction: The prognosis of juvenile idiopathic arthritis (JIA) has changed dramatically due to the availability of novel drugs. Prompt diagnosis and treatment are essential to prevent permanent joint damage. As a result, methods to improve JIA diagnosis and prognosis are of high priority to tailor treatment strategies and maximize their efficacy. Musculoskeletal ultrasound and magnetic resonance imaging are more sensitive than clinical examination and radiography in the detection of joint involvement and might play a substantial role to optimize the management of JIA. Areas covered: This review compiles an inventory of potential uses of imaging studies in the modern practice of pediatric rheumatology, together with a critical analysis of the major challenges that are still to be addressed. Imaging appearance of normal growth-related changes of the musculoskeletal system will be discussed. Expert commentary: Knowledge of the evolving patterns of skeletal maturity is paramount to define pathological findings and avoid misinterpretations. Establishing a novel radiological algorithm for a rational use of imaging in JIA is of high priority to allow a speedier integration of imaging into the clinical workflow and decision-making process.

Original languageEnglish
Pages (from-to)681-694
Number of pages14
JournalExpert Review of Clinical Immunology
Volume14
Issue number8
DOIs
Publication statusPublished - Aug 3 2018

Fingerprint

Juvenile Arthritis
Joints
Musculoskeletal System
Workflow
Rheumatology
Radiography
Magnetic Resonance Imaging
Pediatrics
Equipment and Supplies
Growth
Pharmaceutical Preparations

Keywords

  • Conventional Radiography
  • Growing skeleton
  • Imaging outcome measures
  • Juvenile idiopathic arthritis
  • Magnetic Resonance Imaging
  • Musculoskeletal Ultrasound
  • Remission
  • Structural damage progression

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

The role of imaging in juvenile idiopathic arthritis. / Malattia, Clara; Rinaldi, Mariangela; Martini, Alberto.

In: Expert Review of Clinical Immunology, Vol. 14, No. 8, 03.08.2018, p. 681-694.

Research output: Contribution to journalReview article

@article{53d669b62c0648c1ada27506e8c9bacd,
title = "The role of imaging in juvenile idiopathic arthritis",
abstract = "Introduction: The prognosis of juvenile idiopathic arthritis (JIA) has changed dramatically due to the availability of novel drugs. Prompt diagnosis and treatment are essential to prevent permanent joint damage. As a result, methods to improve JIA diagnosis and prognosis are of high priority to tailor treatment strategies and maximize their efficacy. Musculoskeletal ultrasound and magnetic resonance imaging are more sensitive than clinical examination and radiography in the detection of joint involvement and might play a substantial role to optimize the management of JIA. Areas covered: This review compiles an inventory of potential uses of imaging studies in the modern practice of pediatric rheumatology, together with a critical analysis of the major challenges that are still to be addressed. Imaging appearance of normal growth-related changes of the musculoskeletal system will be discussed. Expert commentary: Knowledge of the evolving patterns of skeletal maturity is paramount to define pathological findings and avoid misinterpretations. Establishing a novel radiological algorithm for a rational use of imaging in JIA is of high priority to allow a speedier integration of imaging into the clinical workflow and decision-making process.",
keywords = "Conventional Radiography, Growing skeleton, Imaging outcome measures, Juvenile idiopathic arthritis, Magnetic Resonance Imaging, Musculoskeletal Ultrasound, Remission, Structural damage progression",
author = "Clara Malattia and Mariangela Rinaldi and Alberto Martini",
year = "2018",
month = "8",
day = "3",
doi = "10.1080/1744666X.2018.1496019",
language = "English",
volume = "14",
pages = "681--694",
journal = "Expert Review of Clinical Immunology",
issn = "1744-666X",
publisher = "Expert Reviews Ltd.",
number = "8",

}

TY - JOUR

T1 - The role of imaging in juvenile idiopathic arthritis

AU - Malattia, Clara

AU - Rinaldi, Mariangela

AU - Martini, Alberto

PY - 2018/8/3

Y1 - 2018/8/3

N2 - Introduction: The prognosis of juvenile idiopathic arthritis (JIA) has changed dramatically due to the availability of novel drugs. Prompt diagnosis and treatment are essential to prevent permanent joint damage. As a result, methods to improve JIA diagnosis and prognosis are of high priority to tailor treatment strategies and maximize their efficacy. Musculoskeletal ultrasound and magnetic resonance imaging are more sensitive than clinical examination and radiography in the detection of joint involvement and might play a substantial role to optimize the management of JIA. Areas covered: This review compiles an inventory of potential uses of imaging studies in the modern practice of pediatric rheumatology, together with a critical analysis of the major challenges that are still to be addressed. Imaging appearance of normal growth-related changes of the musculoskeletal system will be discussed. Expert commentary: Knowledge of the evolving patterns of skeletal maturity is paramount to define pathological findings and avoid misinterpretations. Establishing a novel radiological algorithm for a rational use of imaging in JIA is of high priority to allow a speedier integration of imaging into the clinical workflow and decision-making process.

AB - Introduction: The prognosis of juvenile idiopathic arthritis (JIA) has changed dramatically due to the availability of novel drugs. Prompt diagnosis and treatment are essential to prevent permanent joint damage. As a result, methods to improve JIA diagnosis and prognosis are of high priority to tailor treatment strategies and maximize their efficacy. Musculoskeletal ultrasound and magnetic resonance imaging are more sensitive than clinical examination and radiography in the detection of joint involvement and might play a substantial role to optimize the management of JIA. Areas covered: This review compiles an inventory of potential uses of imaging studies in the modern practice of pediatric rheumatology, together with a critical analysis of the major challenges that are still to be addressed. Imaging appearance of normal growth-related changes of the musculoskeletal system will be discussed. Expert commentary: Knowledge of the evolving patterns of skeletal maturity is paramount to define pathological findings and avoid misinterpretations. Establishing a novel radiological algorithm for a rational use of imaging in JIA is of high priority to allow a speedier integration of imaging into the clinical workflow and decision-making process.

KW - Conventional Radiography

KW - Growing skeleton

KW - Imaging outcome measures

KW - Juvenile idiopathic arthritis

KW - Magnetic Resonance Imaging

KW - Musculoskeletal Ultrasound

KW - Remission

KW - Structural damage progression

UR - http://www.scopus.com/inward/record.url?scp=85052958689&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85052958689&partnerID=8YFLogxK

U2 - 10.1080/1744666X.2018.1496019

DO - 10.1080/1744666X.2018.1496019

M3 - Review article

C2 - 29972659

AN - SCOPUS:85052958689

VL - 14

SP - 681

EP - 694

JO - Expert Review of Clinical Immunology

JF - Expert Review of Clinical Immunology

SN - 1744-666X

IS - 8

ER -