TY - CHAP
T1 - The role of inflammation in Lymphoma
AU - Carbone, Antonino
AU - Tripodo, Claudio
AU - Carlo-Stella, Carmelo
AU - Santoro, Armando
AU - Gloghini, Annunziata
PY - 2014
Y1 - 2014
N2 - Human lymphomas usually develop in specialized tissue microenvironments characterized by different populations of accessory stromal and lymphoid cells that interact with malignant cells. A clinical role of the tumor microenvironment has recently emerged, bringing new knowledge and suggesting new ideas and targets for treatment. This chapter analyzes the microenvironment in human lymphomas highlighting the role of inflammation in their pathogenesis. Microenvironmental specificity is detailed according to different models including classic Hodgkin lymphoma (HL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), peripheral T-cell lymphoma, unspecified and angioimmunoblastic T-cell lymphoma (AITL).
AB - Human lymphomas usually develop in specialized tissue microenvironments characterized by different populations of accessory stromal and lymphoid cells that interact with malignant cells. A clinical role of the tumor microenvironment has recently emerged, bringing new knowledge and suggesting new ideas and targets for treatment. This chapter analyzes the microenvironment in human lymphomas highlighting the role of inflammation in their pathogenesis. Microenvironmental specificity is detailed according to different models including classic Hodgkin lymphoma (HL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), peripheral T-cell lymphoma, unspecified and angioimmunoblastic T-cell lymphoma (AITL).
UR - http://www.scopus.com/inward/record.url?scp=84906910914&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84906910914&partnerID=8YFLogxK
U2 - 10.1007/978-3-0348-0837-8-12
DO - 10.1007/978-3-0348-0837-8-12
M3 - Chapter
C2 - 24818728
SN - 9783034808361
VL - 816
T3 - Advances in Experimental Medicine and Biology
SP - 315
EP - 333
BT - Advances in Experimental Medicine and Biology
ER -