The role of inflammation in Lymphoma

Antonino Carbone, Claudio Tripodo, Carmelo Carlo-Stella, Armando Santoro, Annunziata Gloghini

Research output: Chapter in Book/Report/Conference proceedingChapter


Human lymphomas usually develop in specialized tissue microenvironments characterized by different populations of accessory stromal and lymphoid cells that interact with malignant cells. A clinical role of the tumor microenvironment has recently emerged, bringing new knowledge and suggesting new ideas and targets for treatment. This chapter analyzes the microenvironment in human lymphomas highlighting the role of inflammation in their pathogenesis. Microenvironmental specificity is detailed according to different models including classic Hodgkin lymphoma (HL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), peripheral T-cell lymphoma, unspecified and angioimmunoblastic T-cell lymphoma (AITL).

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
Number of pages19
Publication statusPublished - 2014

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)00652598
ISSN (Electronic)22148019

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)


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