Abstract
Thirty patients with definite multiple sclerosis (MS) were examined monthly for one year. Each time, neurological examination, clinical history and monoclonal-antibody-defined Τ cell subsets were evaluated. Particularly, the helper/suppressor ratio (T4/T8) and the T4/T8 test-to-test variability (ΔΤ4/Τ8) were considered in relation to the occurrence of clinical exacerbations. Statistically significant correlations were found between clinical course and laboratory parameters, suggesting a possible role of Τ cell subset analysis in defining the clinical evolution of MS.
Original language | English |
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Pages (from-to) | 5-12 |
Number of pages | 8 |
Journal | European Neurology |
Volume | 27 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1987 |
Keywords
- Clinical follow-up
- Monoclonal antibodies
- Multiple sclerosis
- Τ cell subsets
ASJC Scopus subject areas
- Clinical Neurology
- Neurology