Abstract
Thirty patients with definite multiple sclerosis (MS) were examined monthly for one year. Each time, neurological examination, clinical history and monoclonal-antibody-defined Τ cell subsets were evaluated. Particularly, the helper/suppressor ratio (T4/T8) and the T4/T8 test-to-test variability (ΔΤ4/Τ8) were considered in relation to the occurrence of clinical exacerbations. Statistically significant correlations were found between clinical course and laboratory parameters, suggesting a possible role of Τ cell subset analysis in defining the clinical evolution of MS.
| Original language | English |
|---|---|
| Pages (from-to) | 5-12 |
| Number of pages | 8 |
| Journal | European Neurology |
| Volume | 27 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1987 |
Keywords
- Clinical follow-up
- Monoclonal antibodies
- Multiple sclerosis
- Τ cell subsets
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
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Cite this
Cazzullo, C. L., Caputo, D., Ghezzi, A., & Zaffaroni, M. (1987). The role of lymphocyte subset analysis in defining the clinical evolution of multiple sclerosis. European Neurology, 27(1), 5-12. https://doi.org/10.1159/000116121