The role of magnetic resonance in the assessment of multiple sclerosis

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Although the correlations between magnetic resonance imaging (MRI) findings and long-term disease evolution range from poor to moderate, conventional pre- and post-contrast MRI provides sensitive and reliable measures to monitor multiple sclerosis (MS) activity over time. MRI pulse sequences that have been recently introduced have shorter acquisition times and their use in large-scale studies can significantly decrease their costs in terms of both working load and patients' discomfort. The application of non-conventional techniques can increase the pathological specificity of MRI findings and, as a consequence, improve the relationship with the clinical evolution of the disease. These techniques also enable us to quantify the subtle abnormalities occuring in the so-called normal-appearing white matter, thus allowing a more accurate assessment of MS burden to be achieved. Some of these techniques have already shown their value for assessing MS dynamics, whereas other still need to go through a more complete validation process prior to any extensive clinical application in MS. Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish
JournalJournal of the Neurological Sciences
Volume172
Issue numberSUPPL. 1
DOIs
Publication statusPublished - Jan 15 2000

Fingerprint

Multiple Sclerosis
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Costs and Cost Analysis

Keywords

  • Diffusion-weighted imaging
  • Magnetic resonance imaging
  • Magnetic resonance spectroscopy
  • Magnetization transfer imaging
  • Multiple sclerosis

ASJC Scopus subject areas

  • Ageing
  • Clinical Neurology
  • Surgery
  • Neuroscience(all)
  • Developmental Neuroscience
  • Neurology

Cite this

The role of magnetic resonance in the assessment of multiple sclerosis. / Rovaris, Marco; Filippi, Massimo.

In: Journal of the Neurological Sciences, Vol. 172, No. SUPPL. 1, 15.01.2000.

Research output: Contribution to journalArticle

@article{33e7bd90564d467cb79478b8aa2af498,
title = "The role of magnetic resonance in the assessment of multiple sclerosis",
abstract = "Although the correlations between magnetic resonance imaging (MRI) findings and long-term disease evolution range from poor to moderate, conventional pre- and post-contrast MRI provides sensitive and reliable measures to monitor multiple sclerosis (MS) activity over time. MRI pulse sequences that have been recently introduced have shorter acquisition times and their use in large-scale studies can significantly decrease their costs in terms of both working load and patients' discomfort. The application of non-conventional techniques can increase the pathological specificity of MRI findings and, as a consequence, improve the relationship with the clinical evolution of the disease. These techniques also enable us to quantify the subtle abnormalities occuring in the so-called normal-appearing white matter, thus allowing a more accurate assessment of MS burden to be achieved. Some of these techniques have already shown their value for assessing MS dynamics, whereas other still need to go through a more complete validation process prior to any extensive clinical application in MS. Copyright (C) 2000 Elsevier Science B.V.",
keywords = "Diffusion-weighted imaging, Magnetic resonance imaging, Magnetic resonance spectroscopy, Magnetization transfer imaging, Multiple sclerosis",
author = "Marco Rovaris and Massimo Filippi",
year = "2000",
month = "1",
day = "15",
doi = "10.1016/S0022-510X(99)00270-1",
language = "English",
volume = "172",
journal = "Journal of the Neurological Sciences",
issn = "0022-510X",
publisher = "Elsevier",
number = "SUPPL. 1",

}

TY - JOUR

T1 - The role of magnetic resonance in the assessment of multiple sclerosis

AU - Rovaris, Marco

AU - Filippi, Massimo

PY - 2000/1/15

Y1 - 2000/1/15

N2 - Although the correlations between magnetic resonance imaging (MRI) findings and long-term disease evolution range from poor to moderate, conventional pre- and post-contrast MRI provides sensitive and reliable measures to monitor multiple sclerosis (MS) activity over time. MRI pulse sequences that have been recently introduced have shorter acquisition times and their use in large-scale studies can significantly decrease their costs in terms of both working load and patients' discomfort. The application of non-conventional techniques can increase the pathological specificity of MRI findings and, as a consequence, improve the relationship with the clinical evolution of the disease. These techniques also enable us to quantify the subtle abnormalities occuring in the so-called normal-appearing white matter, thus allowing a more accurate assessment of MS burden to be achieved. Some of these techniques have already shown their value for assessing MS dynamics, whereas other still need to go through a more complete validation process prior to any extensive clinical application in MS. Copyright (C) 2000 Elsevier Science B.V.

AB - Although the correlations between magnetic resonance imaging (MRI) findings and long-term disease evolution range from poor to moderate, conventional pre- and post-contrast MRI provides sensitive and reliable measures to monitor multiple sclerosis (MS) activity over time. MRI pulse sequences that have been recently introduced have shorter acquisition times and their use in large-scale studies can significantly decrease their costs in terms of both working load and patients' discomfort. The application of non-conventional techniques can increase the pathological specificity of MRI findings and, as a consequence, improve the relationship with the clinical evolution of the disease. These techniques also enable us to quantify the subtle abnormalities occuring in the so-called normal-appearing white matter, thus allowing a more accurate assessment of MS burden to be achieved. Some of these techniques have already shown their value for assessing MS dynamics, whereas other still need to go through a more complete validation process prior to any extensive clinical application in MS. Copyright (C) 2000 Elsevier Science B.V.

KW - Diffusion-weighted imaging

KW - Magnetic resonance imaging

KW - Magnetic resonance spectroscopy

KW - Magnetization transfer imaging

KW - Multiple sclerosis

UR - http://www.scopus.com/inward/record.url?scp=0033992424&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033992424&partnerID=8YFLogxK

U2 - 10.1016/S0022-510X(99)00270-1

DO - 10.1016/S0022-510X(99)00270-1

M3 - Article

VL - 172

JO - Journal of the Neurological Sciences

JF - Journal of the Neurological Sciences

SN - 0022-510X

IS - SUPPL. 1

ER -