The role of nanostructure in the wetting behavior of mixed-monolayer- protected metal nanoparticles

A. Centrone, E. Penzo, M. Sharma, J. W. Myerson, A. M. Jackson, N. Marzari, F. Stellacci

Research output: Contribution to journalArticlepeer-review


Self-assembled monolayer-protected nanoparticles are promising candidates for applications, such as sensing and drug delivery, in which the molecular ligands' interactions with the surrounding environment play a crucial role. We recently showed that, when gold nanoparticles are coated with a binary mixture of immiscible ligands, ordered ribbon-like domains of alternating composition spontaneously form and that their width is comparable with the size of a single solvent molecule. It is usually assumed that nanoparticles' solubility depends solely on the core size and on the molecular composition of the ligand shell. Here, we show that this is not always the case. We find that the ligand shell morphology affects the solubility of these nanoparticles almost as much as the molecular composition. A possible explanation is offered through a molecular dynamics analysis of the surface energy of monolayers differing only in their domain structure. We find that the surface free energy of such model systems can vary significantly as a function of ordering, even at fixed composition. This combined experimental and theoretical study provides a unique insight into wetting phenomena at the nano- and subnanometer scale.

Original languageEnglish
Pages (from-to)9886-9891
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number29
Publication statusPublished - Jul 22 2008


  • Molecular dynamics
  • Phase-separation
  • Self-assembled monolayers
  • Solubility
  • Surface energy

ASJC Scopus subject areas

  • Genetics
  • General


Dive into the research topics of 'The role of nanostructure in the wetting behavior of mixed-monolayer- protected metal nanoparticles'. Together they form a unique fingerprint.

Cite this