Abstract
Reactive oxygen species (ROS) are physiologically produced by the cells. On the other hand, the deleterious effects of ROS are counteracted by the coordinated action of the antioxidant network. Recent works underline the active role of the ROS on several intracellular pathways, where they act as signal transducers. Aim of the present work was to provide an overview of the current literature on the role of the ROS as intracellular mediators, with particular attention to the cellular components of the immune system. Some short considerations about known oxidative stress-related diseases and the possible therapeutical use of antioxidants conclude the paper.
| Original language | Italian |
|---|---|
| Pages (from-to) | 53-66 |
| Number of pages | 14 |
| Journal | Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale |
| Volume | 59 |
| Issue number | 2 |
| Publication status | Published - May 2005 |
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ASJC Scopus subject areas
- Dermatology
Cite this
Il ruolo dello stress ossidativo nella risposta immune. / Dell'Anna, Maria Lucia; Mastrofrancesco, Arianna; Albanesi, Veronica; Picardo, Mauro.
In: Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale, Vol. 59, No. 2, 05.2005, p. 53-66.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Il ruolo dello stress ossidativo nella risposta immune
AU - Dell'Anna, Maria Lucia
AU - Mastrofrancesco, Arianna
AU - Albanesi, Veronica
AU - Picardo, Mauro
PY - 2005/5
Y1 - 2005/5
N2 - Reactive oxygen species (ROS) are physiologically produced by the cells. On the other hand, the deleterious effects of ROS are counteracted by the coordinated action of the antioxidant network. Recent works underline the active role of the ROS on several intracellular pathways, where they act as signal transducers. Aim of the present work was to provide an overview of the current literature on the role of the ROS as intracellular mediators, with particular attention to the cellular components of the immune system. Some short considerations about known oxidative stress-related diseases and the possible therapeutical use of antioxidants conclude the paper.
AB - Reactive oxygen species (ROS) are physiologically produced by the cells. On the other hand, the deleterious effects of ROS are counteracted by the coordinated action of the antioxidant network. Recent works underline the active role of the ROS on several intracellular pathways, where they act as signal transducers. Aim of the present work was to provide an overview of the current literature on the role of the ROS as intracellular mediators, with particular attention to the cellular components of the immune system. Some short considerations about known oxidative stress-related diseases and the possible therapeutical use of antioxidants conclude the paper.
KW - Enzymatic antioxidant
KW - Immune system
KW - Lymphocytic activation
KW - Oxidative stress
KW - Radical species
UR - http://www.scopus.com/inward/record.url?scp=27544443371&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=27544443371&partnerID=8YFLogxK
M3 - Articolo
VL - 59
SP - 53
EP - 66
JO - Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale
JF - Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale
SN - 1592-6826
IS - 2
ER -