Il ruolo dello stress ossidativo nella risposta immune

Translated title of the contribution: The role of oxidative stress in immune system

Research output: Contribution to journalArticle

Abstract

Reactive oxygen species (ROS) are physiologically produced by the cells. On the other hand, the deleterious effects of ROS are counteracted by the coordinated action of the antioxidant network. Recent works underline the active role of the ROS on several intracellular pathways, where they act as signal transducers. Aim of the present work was to provide an overview of the current literature on the role of the ROS as intracellular mediators, with particular attention to the cellular components of the immune system. Some short considerations about known oxidative stress-related diseases and the possible therapeutical use of antioxidants conclude the paper.

Original languageItalian
Pages (from-to)53-66
Number of pages14
JournalAnnali Italiani di Dermatologia Allergologica Clinica e Sperimentale
Volume59
Issue number2
Publication statusPublished - May 2005

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Immune System
Reactive Oxygen Species
Oxidative Stress
Antioxidants
Transducers

ASJC Scopus subject areas

  • Dermatology

Cite this

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title = "Il ruolo dello stress ossidativo nella risposta immune",
abstract = "Reactive oxygen species (ROS) are physiologically produced by the cells. On the other hand, the deleterious effects of ROS are counteracted by the coordinated action of the antioxidant network. Recent works underline the active role of the ROS on several intracellular pathways, where they act as signal transducers. Aim of the present work was to provide an overview of the current literature on the role of the ROS as intracellular mediators, with particular attention to the cellular components of the immune system. Some short considerations about known oxidative stress-related diseases and the possible therapeutical use of antioxidants conclude the paper.",
keywords = "Enzymatic antioxidant, Immune system, Lymphocytic activation, Oxidative stress, Radical species",
author = "Dell'Anna, {Maria Lucia} and Arianna Mastrofrancesco and Veronica Albanesi and Mauro Picardo",
year = "2005",
month = "5",
language = "Italian",
volume = "59",
pages = "53--66",
journal = "Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale",
issn = "1592-6826",
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TY - JOUR

T1 - Il ruolo dello stress ossidativo nella risposta immune

AU - Dell'Anna, Maria Lucia

AU - Mastrofrancesco, Arianna

AU - Albanesi, Veronica

AU - Picardo, Mauro

PY - 2005/5

Y1 - 2005/5

N2 - Reactive oxygen species (ROS) are physiologically produced by the cells. On the other hand, the deleterious effects of ROS are counteracted by the coordinated action of the antioxidant network. Recent works underline the active role of the ROS on several intracellular pathways, where they act as signal transducers. Aim of the present work was to provide an overview of the current literature on the role of the ROS as intracellular mediators, with particular attention to the cellular components of the immune system. Some short considerations about known oxidative stress-related diseases and the possible therapeutical use of antioxidants conclude the paper.

AB - Reactive oxygen species (ROS) are physiologically produced by the cells. On the other hand, the deleterious effects of ROS are counteracted by the coordinated action of the antioxidant network. Recent works underline the active role of the ROS on several intracellular pathways, where they act as signal transducers. Aim of the present work was to provide an overview of the current literature on the role of the ROS as intracellular mediators, with particular attention to the cellular components of the immune system. Some short considerations about known oxidative stress-related diseases and the possible therapeutical use of antioxidants conclude the paper.

KW - Enzymatic antioxidant

KW - Immune system

KW - Lymphocytic activation

KW - Oxidative stress

KW - Radical species

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M3 - Articolo

VL - 59

SP - 53

EP - 66

JO - Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale

JF - Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale

SN - 1592-6826

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