Reactive oxygen species (ROS) are physiologically produced by the cells. On the other hand, the deleterious effects of ROS are counteracted by the coordinated action of the antioxidant network. Recent works underline the active role of the ROS on several intracellular pathways, where they act as signal transducers. Aim of the present work was to provide an overview of the current literature on the role of the ROS as intracellular mediators, with particular attention to the cellular components of the immune system. Some short considerations about known oxidative stress-related diseases and the possible therapeutical use of antioxidants conclude the paper.
|Translated title of the contribution||The role of oxidative stress in immune system|
|Number of pages||14|
|Journal||Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale|
|Publication status||Published - May 2005|
ASJC Scopus subject areas