Abstract
Background: A complete biochemical response (BR) immediately after surgery could be considered an indicator of optimal cancer control after radical prostatectomy (RP). Objective: To evaluate the prognostic value of early postoperative prostate-specific antigen (PSA) levels after RP in patients with lymph node invasion (LNI). Design, setting, and participants: The study included 319 prostate cancer patients with LNI who were treated with RP and extended pelvic lymph node dissection (ePLND) at a single institution between 1998 and 2013. All men had complete clinical, pathologic, and follow-up data, including PSA value at 6 wk after surgery. Patients were divided into two groups according to PSA value at 6 wk after surgery: complete BR (PSA
Original language | English |
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Journal | European Urology |
DOIs | |
Publication status | Accepted/In press - 2015 |
Keywords
- Biochemical response
- Cancer-specific mortality
- Clinical recurrence
- Lymph node invasion
- Prostate cancer
- PSA persistence
- Radical prostatectomy
ASJC Scopus subject areas
- Urology