The role of surgery for haematologic neoplasms of bone

Andreas F. Mavrogenis, Andrea Angelini, Elisa Pala, Pietro Ruggieri, Pierluigi Zinzani

Research output: Contribution to journalArticlepeer-review


We report on 205 patients with haematologic neoplasms of bone treated from 1985 to 2009. There were 77 patients with primary bone lymphoma, 77 with myeloma and 51 with plasmacytoma. All patients had medical treatments 43 patients had wide and 162 intralesional surgery. Mean follow-up was 5 years (median, 3.5 years) 11 patients were lost to followup. At the latest examination, 99 patients were alive without disease, 20 were alive with disease and 75 were dead of disease 13 patients (6.7%) had local recurrence 12 patients (24%) with plasmacytoma developed myeloma. Survival to death was significantly higher after wide resection for lymphoma and plasmacytoma, but not for myeloma. Survival to local recurrence was not statistically different between wide and intralesional surgery for any haematologic neoplasm. Surgical complications including aseptic loosening, infection, neurological deficits and breakage of implants occurred in 21 patients (11%).

Original languageEnglish
Pages (from-to)382-392
Number of pages11
JournalActa Orthopaedica Belgica
Issue number3
Publication statusPublished - 2012


  • Myeloma
  • Plasmacytoma
  • Primary bone lymphoma
  • Surgery
  • Survival.

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


Dive into the research topics of 'The role of surgery for haematologic neoplasms of bone'. Together they form a unique fingerprint.

Cite this