VALIDITA DEL TRATTAMENTO CHIRURGICO NEL CARCINOMA POLMONARE NON A PICCOLE CELLULE CON INVASIONE DEI LINFONODI MEDIASTINICI (N2)

Translated title of the contribution: The role of surgery in non-oat cell lung carcinoma with ipsilateral mediastinal lymph node metastasis

A. Zanella, A. Marchet, F. Favretti, F. De Marchi, D. Nitti

Research output: Contribution to journalArticle

Abstract

A review is made of the results of surgery in 27 patients with non oat-cell carcinoma of the lung and metastasis to the ipsilateral mediastinal lymph nodes (N2) at the pathologic staging. Potentially curative resection was performed in all cases despite the presence of mediastinal lymph node metastases. Six patients had T1, 19 had T2 and two had T3 tumors. Six patients had single mediastinal lymph node metastases, 21 had multiple node involvement. Hilar lymph nodes were negative in 9/27 cases (33%). The three-year actuarial survival was 44% after a mean follow-up of 22.1 months (range 3-76 months). Ten patients died with distant metastases and 17 are still alive. Surgery can therefore be performed for non oat-cell carcinoma of the lung with ipsilateral mediastinal lymph node metastasis (N2). However, in view of the high incidence of distant metastasis, adjuvant systemic therapy is advisable.

Original languageItalian
Pages (from-to)25-27
Number of pages3
JournalChirurgia
Volume7
Issue number1-2
Publication statusPublished - 1994

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Lymph Nodes
Neoplasm Metastasis
Carcinoma
Lung
Small Cell Lung Carcinoma
Survival
Incidence
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Zanella, A., Marchet, A., Favretti, F., De Marchi, F., & Nitti, D. (1994). VALIDITA DEL TRATTAMENTO CHIRURGICO NEL CARCINOMA POLMONARE NON A PICCOLE CELLULE CON INVASIONE DEI LINFONODI MEDIASTINICI (N2). Chirurgia, 7(1-2), 25-27.

VALIDITA DEL TRATTAMENTO CHIRURGICO NEL CARCINOMA POLMONARE NON A PICCOLE CELLULE CON INVASIONE DEI LINFONODI MEDIASTINICI (N2). / Zanella, A.; Marchet, A.; Favretti, F.; De Marchi, F.; Nitti, D.

In: Chirurgia, Vol. 7, No. 1-2, 1994, p. 25-27.

Research output: Contribution to journalArticle

Zanella, A, Marchet, A, Favretti, F, De Marchi, F & Nitti, D 1994, 'VALIDITA DEL TRATTAMENTO CHIRURGICO NEL CARCINOMA POLMONARE NON A PICCOLE CELLULE CON INVASIONE DEI LINFONODI MEDIASTINICI (N2)', Chirurgia, vol. 7, no. 1-2, pp. 25-27.
Zanella, A. ; Marchet, A. ; Favretti, F. ; De Marchi, F. ; Nitti, D. / VALIDITA DEL TRATTAMENTO CHIRURGICO NEL CARCINOMA POLMONARE NON A PICCOLE CELLULE CON INVASIONE DEI LINFONODI MEDIASTINICI (N2). In: Chirurgia. 1994 ; Vol. 7, No. 1-2. pp. 25-27.
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AB - A review is made of the results of surgery in 27 patients with non oat-cell carcinoma of the lung and metastasis to the ipsilateral mediastinal lymph nodes (N2) at the pathologic staging. Potentially curative resection was performed in all cases despite the presence of mediastinal lymph node metastases. Six patients had T1, 19 had T2 and two had T3 tumors. Six patients had single mediastinal lymph node metastases, 21 had multiple node involvement. Hilar lymph nodes were negative in 9/27 cases (33%). The three-year actuarial survival was 44% after a mean follow-up of 22.1 months (range 3-76 months). Ten patients died with distant metastases and 17 are still alive. Surgery can therefore be performed for non oat-cell carcinoma of the lung with ipsilateral mediastinal lymph node metastasis (N2). However, in view of the high incidence of distant metastasis, adjuvant systemic therapy is advisable.

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