The role of surgery in the treatment of pituitary tumors

P. Martini, M. Losa, A. Franzin, R. Barzaghi, M. Giovanelli

Research output: Contribution to journalArticlepeer-review


Aim of the study: To evaluate the efficacy and safety of surgical treatment of pituitary tumors compared to other therapies. Material and methods: Between 1990 and 1999, 1004 patients were operated in our institution for pituitary adenoma; 310 transphenoidal operations were performed on non-secreting adenomas, 277 on GH-secreting adenomas, 134 on prolactinomas, 230 on ACTH-secreting adenomas, and 24 on TSH-omas; 20 transcranial operations were done on nonsecreting adenomas, 3 on GH-secreting adenomas, 1 on prolactinomas, 4 on ACTH secreting adenomas, and 2 on TSHomas. The transcranial operation was done through the pterional approach in 23 patients through the subfrontal in 2 and fronto-orbital approach in 5. A total of 974 patients were operated through the transphenoidal route and only 30 were operated through a transcranial route. The first operations were 858 (844 transphenoidal and 14 transcranial) and the second operations were 146 (130 transphenoidal and 16 transcranial). The criteria of cure in GH-secreting adenomas were; GH

Original languageEnglish
Pages (from-to)16-17
Number of pages2
JournalSkull Base
Issue numberSUPPL. 2
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Clinical Neurology

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