Il ruolo della terapia chirurgica nel microcitoma dell'esofago: Esperienza di tre casi clinici ed analisi dei risultati

Translated title of the contribution: The role of surgical therapy for esophageal microcytoma: Experience of three clinical cases and results analysis

P. P. Brega-Massone, B. Conti, C. Lequaglie, F. Ferro, I. Cataldo

Research output: Contribution to journalArticle

Abstract

Small cell carcinoma of the esophagus is a rare tumor. It was described for the first time in 1952 by McKeown and 200 cases have been reported till now. Because of its similarity with small cell carcinoma of the lung, the treatment of this tumor is controversial. In our Institute we treated three patients with small cell carcinoma of the esophagus. All subjects underwent subtotal esophagectomy with esophagogastroanastomosis through laparotomic and thoracotomic approach. Histologically, the tumor was classified as pure SCEC in one patient and mixed SCEC in the other two. The stage I and H patients received operation as single treatment. The two patients are alive and disease free 219 and 193 months after surgery. The third patient, classified at stage HI, underwent postoperative chemotherapy but local and distant recurrence was observed 11 months after surgical resection. He was submitted to a second choice chemotherapy, but he died 24 months after the operation. The long-term survival observed in our two patients treated by surgery is the longest described in literature. Our experience seems to demonstrate that an early diagnosis and oncological radical resection, may be helpful in the long-term prognosis even in presence of a very aggressive neoplasm.

Original languageItalian
Pages (from-to)629-632
Number of pages4
JournalMinerva Chirurgica
Volume58
Issue number4
Publication statusPublished - Aug 2003

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ASJC Scopus subject areas

  • Surgery

Cite this

Brega-Massone, P. P., Conti, B., Lequaglie, C., Ferro, F., & Cataldo, I. (2003). Il ruolo della terapia chirurgica nel microcitoma dell'esofago: Esperienza di tre casi clinici ed analisi dei risultati. Minerva Chirurgica, 58(4), 629-632.