The role of the dorsal striatum in the recognition of emotions expressed by voice in Parkinson’s disease

Sonia Di Tella, Isabella Anzuino, Federica Biassoni, Maria Rita Ciceri, Martina Gnerre, Raffaello Nemni, Monia Cabinio, Francesca Baglio, Maria Caterina Silveri

Research output: Contribution to journalArticlepeer-review

Abstract

Background and purpose: Non-motor impairment such as emotion recognition deficit in both facial and vocal expressions has been previously reported in Parkinson’s disease (PD). We investigated whether the decoding of emotional prosody is impaired in PD and whether this deficit is related to striatal damage. Methods: Fifteen PD patients and 15 healthy controls (HCs) were requested to listen to six audio tracks and to recognize the emotions expressed by a professional actor while reading a meaning-neutral sentence. All subjects also received a structural MRI examination. Volumetric measurements were extracted for the striatum, a key region involved in emotional processing and typically impaired in PD. Results: Decoding sadness conveyed by voice was impaired in PD compared with HC and was related to the volume of the dorsal striatum bilaterally. Conclusions: The dorsal striatum is involved in the decoding of vocal negative emotions in PD.

Original languageEnglish
JournalNeurological Sciences
DOIs
Publication statusAccepted/In press - 2021

Keywords

  • Dorsal striatum
  • Emotional prosody
  • Negative emotions
  • Parkinson’s disease (PD)
  • Recognition of emotions
  • Structural MRI

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

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