The role of the left frontal lobe in action naming rTMS evidence

S. F. Cappa, M. Sandrini, P. M. Rossini, K. Sosta, C. Miniussi

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Neuropsychological and neuroimaging studies suggest that whereas the left temporal neocortex plays a crucial role in all tasks involving lexical-semantic processing, some regions of the left prefrontal convexity are selectively recruited during verb processing. Objective: To determine if there are different neural correlates for noun and verb processing in the human brain. Methods: Repetitive transcranial magnetic stimulation (rTMS), 20 Hz at 90% of the motor threshold, was applied to left or right prefrontal brain during object- and action-naming tasks in nine healthy subjects. Results: A shortening of naming latency for actions was observed only after stimulation of left prefrontal cortex. Conclusion: The involvement of the left dorsolateral frontal cortex in action naming was demonstrated using rTMS.

Original languageEnglish
Pages (from-to)720-723
Number of pages4
JournalNeurology
Volume59
Issue number5
Publication statusPublished - Sep 10 2002

ASJC Scopus subject areas

  • Neuroscience(all)

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