The saliva quantitative PCR assay is inadequate to detect and monitor human herpesvirus-7 and -6 reactivation in patients with Pityriasis rosea

Francesco Broccolo, Giulia Ciccarese, Massimo Oggioni, Alfredo Rebora, Aurora Parodi, Francesco Drago

Research output: Contribution to journalArticlepeer-review

Abstract

The endogenous reactivation of HHV-6/7 may result in Pityriasis rosea (PR). The blood viral load distinguishes between latent and clinically manifest disease. We compared HHV-7/6 DNA load in saliva and blood samples of PR patients and controls. Salivary PCR assay is inadequate to detect and follow-up HHV-7 reactivation in PR. Only the plasma viral DNA load remains the direct marker of the viral replication.

Original languageEnglish
Pages (from-to)615-616
Number of pages2
JournalJournal of Clinical Virology
Volume61
Issue number4
DOIs
Publication statusPublished - 2014

Keywords

  • Herpesviruses
  • HHV-6
  • HHV-7
  • Plasma viremia
  • Reactivation
  • Saliva

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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