The science behind vitamins and natural compounds for breast cancer prevention. Getting the most prevention out of it

Matteo Lazzeroni, Sara Gandini, Matteo Puntoni, Bernardo Bonanni, Alessandra Gennari, Andrea DeCensi

Research output: Contribution to journalArticlepeer-review

Abstract

Summary: This review highlights the role of vitamins and natural compounds in breast cancer prevention, with a particular focus on Vitamin D. In the last decades, both encouraging and discouraging results about the association between antioxidant supplementation and cancer have been reported to public and scientific community. Their safe and favorable toxicity profile makes them suitable to be investigated in a preventive setting. However, a recent large meta-analysis showed that treatment with beta carotene, vitamin A, and vitamin E may increase mortality, whereas the potential roles of vitamin C and selenium on mortality need further study. Likewise, folate levels were not associated with reduced breast cancer risk in a recent meta-analysis. Several studies have shown that a high proportion of women at-risk for breast cancer or affected by the disease have deficient vitamin D levels, i.e., 250H-D

Original languageEnglish
JournalBreast
Volume20
Issue numberSUPPL. 3
DOIs
Publication statusPublished - Oct 2011

Keywords

  • Antioxidants
  • Breast Cancer
  • Chemoprevention
  • Fenretinide
  • Vitamin-D

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'The science behind vitamins and natural compounds for breast cancer prevention. Getting the most prevention out of it'. Together they form a unique fingerprint.

Cite this