The science of stem cell biobanking: Investing in the future

Giuseppe R. Diaferia, Marina Cardano, Monica Cattaneo, Chiara C. Spinelli, Sara S. Dessì, Pasquale Deblasio, Ida Biunno

Research output: Contribution to journalArticlepeer-review

Abstract

The use of human stem cells in biomedical research projects is increasing steadily and the number of cells that are being derived develops at a remarkable pace. However, stem cells around the world are vastly different in their provenance, programming, and potentials. Furthermore, knowledge on the actual number of cell types, their derivation, availability, and characteristics is rather sparse. Usually, "colleague-supply" avenues constantly furnish cells to laboratories around the world without ensuring their correct identity, characterization, and quality. These parameters are critical if the cells will be eventually used in toxicology studies and drug discovery. Here, we outline some basic principles in establishing a stem cell-specific bank.

Original languageEnglish
Pages (from-to)14-19
Number of pages6
JournalJournal of Cellular Physiology
Volume227
Issue number1
DOIs
Publication statusPublished - Jan 2012

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Physiology

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