The sense-of-coherence predicts health-related quality of life and emotional distress but not disability in Parkinson's disease

Annalisa Gison, Federica Rizza, Stefano Bonassi, Valentina Dall'Armi, Stefania Lisi, Salvatore Giaquinto

Research output: Contribution to journalArticle

Abstract

Background: Personality traits are deemed important in many fields of Medicine. The present study aimed at evaluating i) the presence of Sense-of-Coherence (SOC) in patients suffering from Parkinson's Disease (PD) in comparison with an age-matched general control population, ii) the influence of SOC on health-related variables, such as depression and anxiety, quality of life (Qol), and activities of daily living (ADL).Methods: SOC was measured in 50 PD patients and in 50 matched controls enrolled in cross-sectional study. The other clinical measures included: Mini Mental State Examination (MMSE), Movement Disorder Society revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Well-being Index (WHO-5), Hospital Anxiety and Depression Scale (HADS) and the Barthel Index of ADL (BI). Data were analysed with univariate statistics and loglinear adjusted regression models.Results: No difference emerged between PD and controls on socio-demographic and SOC. A statistically significant positive correlation was found between SOC and Qol (0.40, p <0.004) and a negative significant correlation between SOC and emotional distress (-0.37, p <0.008). The multivariate regression analysis confirmed the negative effect of SOC on total emotional distress (-3%, p = 0.01) and positive effect on Qol (2%, p = 0.01). SOC and BI were uncorrelated.Conclusions: SOC is predictive of QoL and emotional distress in PD, whereas no evidence of a predictive effect for disability could be found. These results support only partially, the Salutogenic Theory in PD, i.e. a strong SOC positively influences psychosocial health, but does not influence physical health.

Original languageEnglish
Article number193
JournalBMC Neurology
Volume14
Issue number1
DOIs
Publication statusPublished - Oct 10 2014

Keywords

  • Depression
  • Parkinson's disease
  • Quality of life
  • Sense-of-coherence

ASJC Scopus subject areas

  • Clinical Neurology

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