Abstract
The sequence technique is commonly employed to estimate the baroreflex sensitivity from the analysis of systolic blood pressure (SBP) and RR Interval (RRI) recordings. Traditionally, the RRI+/SBP- and RRI-/SBP+ sequences are excluded from this analysis. In this paper we present a new interpretative model that, through the introduction of the concept of baroreflex SBP set point, proposes a sub-classification of the excluded sequences in " converging" and "diverging" types, depending on whether they point at, or, depart from the SBP set point, respectively. According to the model, also the RRI+/SBP- and RRI-/SBP+ "converging" sequences might be associated with the baroreflex control of circulation. As a first test of the model, we estimated the distribution of the "converging" and "diverging" RRI+/SBP- and RRI-/SBP+ sequences in a group of 10 healthy subjects at rest in a quiet context, where an enhancement of the baroreflex function could be assumed and a predominance of the "converging" sequences could be expected according to the model. Actually the results confirmed a significant prevalence of "converging" type over the "diverging" type sequences (10.6±6.7 vs. 3.3±2.8, mean±sd) in these recordings. Although future studies are needed to experimentally validate this new classification of the RRI+/SBP- and RRI-/SBP+ sequences, our results provide a first positive support to the model.
| Original language | English |
|---|---|
| Title of host publication | 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 |
| Pages | 1703-1705 |
| Number of pages | 3 |
| DOIs | |
| Publication status | Published - 2010 |
| Event | 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina Duration: Aug 31 2010 → Sep 4 2010 |
Other
| Other | 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 |
|---|---|
| Country | Argentina |
| City | Buenos Aires |
| Period | 8/31/10 → 9/4/10 |
Fingerprint
ASJC Scopus subject areas
- Biomedical Engineering
Cite this
The sequence technique revised : Additional concepts on the assessment of spontaneous baroreflex function. / Di Rienzo, M.; Castiglioni, P.; Parati, G.
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. 2010. p. 1703-1705 5626844.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - The sequence technique revised
T2 - Additional concepts on the assessment of spontaneous baroreflex function
AU - Di Rienzo, M.
AU - Castiglioni, P.
AU - Parati, G.
PY - 2010
Y1 - 2010
N2 - The sequence technique is commonly employed to estimate the baroreflex sensitivity from the analysis of systolic blood pressure (SBP) and RR Interval (RRI) recordings. Traditionally, the RRI+/SBP- and RRI-/SBP+ sequences are excluded from this analysis. In this paper we present a new interpretative model that, through the introduction of the concept of baroreflex SBP set point, proposes a sub-classification of the excluded sequences in " converging" and "diverging" types, depending on whether they point at, or, depart from the SBP set point, respectively. According to the model, also the RRI+/SBP- and RRI-/SBP+ "converging" sequences might be associated with the baroreflex control of circulation. As a first test of the model, we estimated the distribution of the "converging" and "diverging" RRI+/SBP- and RRI-/SBP+ sequences in a group of 10 healthy subjects at rest in a quiet context, where an enhancement of the baroreflex function could be assumed and a predominance of the "converging" sequences could be expected according to the model. Actually the results confirmed a significant prevalence of "converging" type over the "diverging" type sequences (10.6±6.7 vs. 3.3±2.8, mean±sd) in these recordings. Although future studies are needed to experimentally validate this new classification of the RRI+/SBP- and RRI-/SBP+ sequences, our results provide a first positive support to the model.
AB - The sequence technique is commonly employed to estimate the baroreflex sensitivity from the analysis of systolic blood pressure (SBP) and RR Interval (RRI) recordings. Traditionally, the RRI+/SBP- and RRI-/SBP+ sequences are excluded from this analysis. In this paper we present a new interpretative model that, through the introduction of the concept of baroreflex SBP set point, proposes a sub-classification of the excluded sequences in " converging" and "diverging" types, depending on whether they point at, or, depart from the SBP set point, respectively. According to the model, also the RRI+/SBP- and RRI-/SBP+ "converging" sequences might be associated with the baroreflex control of circulation. As a first test of the model, we estimated the distribution of the "converging" and "diverging" RRI+/SBP- and RRI-/SBP+ sequences in a group of 10 healthy subjects at rest in a quiet context, where an enhancement of the baroreflex function could be assumed and a predominance of the "converging" sequences could be expected according to the model. Actually the results confirmed a significant prevalence of "converging" type over the "diverging" type sequences (10.6±6.7 vs. 3.3±2.8, mean±sd) in these recordings. Although future studies are needed to experimentally validate this new classification of the RRI+/SBP- and RRI-/SBP+ sequences, our results provide a first positive support to the model.
UR - http://www.scopus.com/inward/record.url?scp=78650810875&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650810875&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2010.5626844
DO - 10.1109/IEMBS.2010.5626844
M3 - Conference contribution
SN - 9781424441235
SP - 1703
EP - 1705
BT - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
ER -