TY - JOUR
T1 - The SF-36 instrument for the follow-up of health-related quality-of-life assessment of patients undergoing home parenteral nutrition for benign disease
AU - Pironi, L.
AU - Paganelli, F.
AU - Mosconi, P.
AU - Morselli-Labate, A. M.
AU - Spinucci, G.
AU - Merli, C.
AU - Guidetti, M.
AU - Miglioli, M.
PY - 2004/3
Y1 - 2004/3
N2 - Introduction The non-disease-specific SF-36 instrument was applied to detect changes in quality of life among patients at a single center who were receiving home parenteral nutrition (HPN) for intestinal failure. Methods All HPN patients completed the questionnaire during routine visits. The SF-36 examines eight domains (scores: 0% to 100%): physical functioning (PF), role-functioning physical (RP), body pain (BP), general health (GH), vitality (VT), social functioning (SF), as well as role-functioning emotional (RE) and mental health (MH). Patient responses were standardized for the sex- and age-matched group scores of the healthy population by calculating the Z-score: (healthy population mean score - patient raw score)/healthy population standard deviation (reduced value: Z-score <-1). A difference in a domain score was considered significant in the individual patient if it was greater than the 90% confidence interval for healthy subjects and if it produced a change in Z-score category. General, sociodemographic, underlying disease and HPN-related factors were collected. Results For 31 enrolled adult patients, the baseline mean Z-score was reduced in five domains: PF, RP, BP, GH and SF. Twenty patients underwent a second SF-36 assessment 10 ± 2 months later: the HRQOL worsened in eight and improved in 10 (no. worsened domains > no. improved or vice versa). The worsened subgroup showed a decrease in body mass index (P = .104), an increase in the number of HPN infusions per week (P = .065), and a greater incidence of intestinal motility disorders (P = .161), of liquid oral diet (P = .027), and of nycturia (P = .028). Conclusions The SF-36 instrument reflecting the generic HRQOL assessment may be a suitable tool for patients on HPN.
AB - Introduction The non-disease-specific SF-36 instrument was applied to detect changes in quality of life among patients at a single center who were receiving home parenteral nutrition (HPN) for intestinal failure. Methods All HPN patients completed the questionnaire during routine visits. The SF-36 examines eight domains (scores: 0% to 100%): physical functioning (PF), role-functioning physical (RP), body pain (BP), general health (GH), vitality (VT), social functioning (SF), as well as role-functioning emotional (RE) and mental health (MH). Patient responses were standardized for the sex- and age-matched group scores of the healthy population by calculating the Z-score: (healthy population mean score - patient raw score)/healthy population standard deviation (reduced value: Z-score <-1). A difference in a domain score was considered significant in the individual patient if it was greater than the 90% confidence interval for healthy subjects and if it produced a change in Z-score category. General, sociodemographic, underlying disease and HPN-related factors were collected. Results For 31 enrolled adult patients, the baseline mean Z-score was reduced in five domains: PF, RP, BP, GH and SF. Twenty patients underwent a second SF-36 assessment 10 ± 2 months later: the HRQOL worsened in eight and improved in 10 (no. worsened domains > no. improved or vice versa). The worsened subgroup showed a decrease in body mass index (P = .104), an increase in the number of HPN infusions per week (P = .065), and a greater incidence of intestinal motility disorders (P = .161), of liquid oral diet (P = .027), and of nycturia (P = .028). Conclusions The SF-36 instrument reflecting the generic HRQOL assessment may be a suitable tool for patients on HPN.
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U2 - 10.1016/j.transproceed.2003.12.008
DO - 10.1016/j.transproceed.2003.12.008
M3 - Article
C2 - 15050126
AN - SCOPUS:1642544142
VL - 36
SP - 255
EP - 258
JO - Transplantation Proceedings
JF - Transplantation Proceedings
SN - 0041-1345
IS - 2
ER -