The short cognitive evaluation battery in cognitive disorders of the elderly - Italian version

Nicola Girtler, Andrea Brugnolo, Claudio Campus, Fabrizio De Carli, Francesco Fam, Lucio Ghio, Philippe Robert, Maria Paola Barbieri, Marta Delmonte, Stefano Venuti, Filippo Gabrielli, Guido Rodriguez, Flavio Nobili

Research output: Contribution to journalArticlepeer-review

Abstract

Aims: To validate the Italian version of the Short Cognitive Evaluation Battery (SCEB), consisting of 4 tests (temporal orientation, five words, clock drawing and verbal fluency) in healthy controls (CONT), patients with mild Alzheimer's disease (AD), mild cognitive impairment (MCI), and major depressive disorder (DEP). Methods: Twenty-nine AD patients (mean Mini-Mental State Examination, MMSE, score: 22.1 ± 3.1), 27 MCI patients (mean MMSE score: 26.5 ± 2.0), 27 depressed patients (mean MMSE score: 26.9 ± 2.8), and 48 controls (mean MMSE score: 29.7 ± 0.5) were enrolled. Results: MANCOVA showed highly significant (p < 0.0001) difference among groups. As for total SCEB score, AD were separated from CONT with high accuracy (93%; with sensitivity 93%, specificity 92%, area under ROC curve, AUC, 0.96) and from DEP with satisfying accuracy (84%; with sensitivity 76%, specificity 93%, AUC 0.84). Results in MCI versus CONT comparison yielded more moderate accuracy (80%; with sensitivity 70%, specificity 87%, AUC 0.80), which increased in the subgroup of MCI patients who later converted to AD (85%; with sensitivity 75%, specificity 83%, AUC 0.86). The direct comparison between MCI converters and nonconverters did not yield accurate results. Conclusion: The Italian version of the SCEB is a short (between 6 min in CONT and 12 min in DEP) screening tool in cognitive disorders of the elderly, and is potentially useful in clinical practice.

Original languageEnglish
Pages (from-to)255-265
Number of pages11
JournalDementia and Geriatric Cognitive Disorders
Volume33
Issue number4
DOIs
Publication statusPublished - Jan 1 2012

Keywords

  • Alzheimer's disease
  • Cognitive screening
  • Depression
  • Mild cognitive impairment
  • Short Cognitive Evaluation Battery

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Cognitive Neuroscience
  • Psychiatry and Mental health

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