The Skin as an Early Expression of Malignancies in the Neonatal Age: A Review of the Literature and a Case Series

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Abstract

Skin lesions are a frequent finding in childhood, from infancy throughout adolescence. They can arise from many conditions, including infections and inflammation. Most neonatal rashes are benign and self-limiting and require no treatment. Other conditions may be an expression of malignancy or may be a marker for other abnormalities, such as neural tube defects. Therefore, skin lesions require an extensive evaluation and close follow-up to ensure the best possible outcome. This paper briefly reviews the main tumor types presenting with cutaneous involvement in neonates, followed by the description of some patients admitted to our Neonatal Intensive Care Unit with an early skin expression of malignancies.

Original languageEnglish
Article number809406
JournalBioMed Research International
Volume2015
DOIs
Publication statusPublished - 2015

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Skin
Intensive care units
Neoplasms
Neural Tube Defects
Tumors
Neonatal Intensive Care Units
Exanthema
Defects
Newborn Infant
Inflammation
Infection
Therapeutics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

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title = "The Skin as an Early Expression of Malignancies in the Neonatal Age: A Review of the Literature and a Case Series",
abstract = "Skin lesions are a frequent finding in childhood, from infancy throughout adolescence. They can arise from many conditions, including infections and inflammation. Most neonatal rashes are benign and self-limiting and require no treatment. Other conditions may be an expression of malignancy or may be a marker for other abnormalities, such as neural tube defects. Therefore, skin lesions require an extensive evaluation and close follow-up to ensure the best possible outcome. This paper briefly reviews the main tumor types presenting with cutaneous involvement in neonates, followed by the description of some patients admitted to our Neonatal Intensive Care Unit with an early skin expression of malignancies.",
author = "Vito Mond{\`i} and Fiammetta Piersigilli and Guglielmo Salvatori and Cinzia Auriti",
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journal = "BioMed Research International",
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