The spectrum of idiopathic rolandic epilepsy syndromes and idiopathic occipital epilepsies

From the benign to the disabling

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Benign childhood epilepsy with centrotemporal spikes (BCECTS) is an idiopathic focal epilepsy syndrome, the benign characteristics of which are debated; in fact, stable or intermittent specific neuropsychological deficits are frequent and may affect scholastic or adaptive abilities. Cognitive dysfunction may be related to a marked increment of the interictal epileptic discharges in NREM sleep: different degrees of neuropsychological deficits depend on the extent of awake and sleep activity and the predominant discharge localization. The age of onset and duration of atypical sleep EEG patterns may correlate with permanent cognitive impairments. These atypical clinical and EEG evolutions have been reported in the literature as different syndromes that constitute the spectrum of idiopathic rolandic epilepsy. Moreover, a clinical link between BCECTS and early-onset benign childhood occipital epilepsy has been demonstrated. According to the neurobiological approach, the spectrum of Idiopathic Rolandic Epilepsy is based on an age-dependent, idiopathic predisposition to focal seizures and sharp-wave discharges, as an expression of nonlesional cortical excitability. The involvement of a given area of the cerebral cortex may depend on the brain maturational stage.

Original languageEnglish
Pages (from-to)62-66
Number of pages5
JournalEpilepsia
Volume47
Issue numberSUPPL. 2
DOIs
Publication statusPublished - Nov 2006

Fingerprint

Rolandic Epilepsy
Partial Epilepsy
Sleep
Electroencephalography
Aptitude
Age of Onset
Cerebral Cortex
Seizures
Brain

Keywords

  • BCECTS
  • Early-onset BCOE
  • Rolandic epilepsy "related disorders"

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

The spectrum of idiopathic rolandic epilepsy syndromes and idiopathic occipital epilepsies : From the benign to the disabling. / Gobbi, Giuseppe; Boni, Antonella; Filippini, Melissa.

In: Epilepsia, Vol. 47, No. SUPPL. 2, 11.2006, p. 62-66.

Research output: Contribution to journalArticle

@article{ffc7d08b3c4d46bd90f9e82109451604,
title = "The spectrum of idiopathic rolandic epilepsy syndromes and idiopathic occipital epilepsies: From the benign to the disabling",
abstract = "Benign childhood epilepsy with centrotemporal spikes (BCECTS) is an idiopathic focal epilepsy syndrome, the benign characteristics of which are debated; in fact, stable or intermittent specific neuropsychological deficits are frequent and may affect scholastic or adaptive abilities. Cognitive dysfunction may be related to a marked increment of the interictal epileptic discharges in NREM sleep: different degrees of neuropsychological deficits depend on the extent of awake and sleep activity and the predominant discharge localization. The age of onset and duration of atypical sleep EEG patterns may correlate with permanent cognitive impairments. These atypical clinical and EEG evolutions have been reported in the literature as different syndromes that constitute the spectrum of idiopathic rolandic epilepsy. Moreover, a clinical link between BCECTS and early-onset benign childhood occipital epilepsy has been demonstrated. According to the neurobiological approach, the spectrum of Idiopathic Rolandic Epilepsy is based on an age-dependent, idiopathic predisposition to focal seizures and sharp-wave discharges, as an expression of nonlesional cortical excitability. The involvement of a given area of the cerebral cortex may depend on the brain maturational stage.",
keywords = "BCECTS, Early-onset BCOE, Rolandic epilepsy {"}related disorders{"}",
author = "Giuseppe Gobbi and Antonella Boni and Melissa Filippini",
year = "2006",
month = "11",
doi = "10.1111/j.1528-1167.2006.00693.x",
language = "English",
volume = "47",
pages = "62--66",
journal = "Epilepsia",
issn = "0013-9580",
publisher = "Blackwell Publishing Inc.",
number = "SUPPL. 2",

}

TY - JOUR

T1 - The spectrum of idiopathic rolandic epilepsy syndromes and idiopathic occipital epilepsies

T2 - From the benign to the disabling

AU - Gobbi, Giuseppe

AU - Boni, Antonella

AU - Filippini, Melissa

PY - 2006/11

Y1 - 2006/11

N2 - Benign childhood epilepsy with centrotemporal spikes (BCECTS) is an idiopathic focal epilepsy syndrome, the benign characteristics of which are debated; in fact, stable or intermittent specific neuropsychological deficits are frequent and may affect scholastic or adaptive abilities. Cognitive dysfunction may be related to a marked increment of the interictal epileptic discharges in NREM sleep: different degrees of neuropsychological deficits depend on the extent of awake and sleep activity and the predominant discharge localization. The age of onset and duration of atypical sleep EEG patterns may correlate with permanent cognitive impairments. These atypical clinical and EEG evolutions have been reported in the literature as different syndromes that constitute the spectrum of idiopathic rolandic epilepsy. Moreover, a clinical link between BCECTS and early-onset benign childhood occipital epilepsy has been demonstrated. According to the neurobiological approach, the spectrum of Idiopathic Rolandic Epilepsy is based on an age-dependent, idiopathic predisposition to focal seizures and sharp-wave discharges, as an expression of nonlesional cortical excitability. The involvement of a given area of the cerebral cortex may depend on the brain maturational stage.

AB - Benign childhood epilepsy with centrotemporal spikes (BCECTS) is an idiopathic focal epilepsy syndrome, the benign characteristics of which are debated; in fact, stable or intermittent specific neuropsychological deficits are frequent and may affect scholastic or adaptive abilities. Cognitive dysfunction may be related to a marked increment of the interictal epileptic discharges in NREM sleep: different degrees of neuropsychological deficits depend on the extent of awake and sleep activity and the predominant discharge localization. The age of onset and duration of atypical sleep EEG patterns may correlate with permanent cognitive impairments. These atypical clinical and EEG evolutions have been reported in the literature as different syndromes that constitute the spectrum of idiopathic rolandic epilepsy. Moreover, a clinical link between BCECTS and early-onset benign childhood occipital epilepsy has been demonstrated. According to the neurobiological approach, the spectrum of Idiopathic Rolandic Epilepsy is based on an age-dependent, idiopathic predisposition to focal seizures and sharp-wave discharges, as an expression of nonlesional cortical excitability. The involvement of a given area of the cerebral cortex may depend on the brain maturational stage.

KW - BCECTS

KW - Early-onset BCOE

KW - Rolandic epilepsy "related disorders"

UR - http://www.scopus.com/inward/record.url?scp=33750598759&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750598759&partnerID=8YFLogxK

U2 - 10.1111/j.1528-1167.2006.00693.x

DO - 10.1111/j.1528-1167.2006.00693.x

M3 - Article

VL - 47

SP - 62

EP - 66

JO - Epilepsia

JF - Epilepsia

SN - 0013-9580

IS - SUPPL. 2

ER -