The Spiritual Brain: Selective Cortical Lesions Modulate Human Self-Transcendence

Cosimo Urgesi, Salvatore M. Aglioti, Miran Skrap, Franco Fabbro

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

The predisposition of human beings toward spiritual feeling, thinking, and behaviors is measured by a supposedly stable personality trait called self-transcendence. Although a few neuroimaging studies suggest that neural activation of a large fronto-parieto-temporal network may underpin a variety of spiritual experiences, information on the causative link between such a network and spirituality is lacking. Combining pre- and post-neurosurgery personality assessment with advanced brain-lesion mapping techniques, we found that selective damage to left and right inferior posterior parietal regions induced a specific increase of self-transcendence. Therefore, modifications of neural activity in temporoparietal areas may induce unusually fast modulations of a stable personality trait related to transcendental self-referential awareness. These results hint at the active, crucial role of left and right parietal systems in determining self-transcendence and cast new light on the neurobiological bases of altered spiritual and religious attitudes and behaviors in neurological and mental disorders.

Original languageEnglish
Pages (from-to)309-319
Number of pages11
JournalNeuron
Volume65
Issue number3
DOIs
Publication statusPublished - Feb 11 2010

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Neurosurgery
Personality
Personality Assessment
Brain Mapping
Parietal Lobe
Spirituality
Brain
Nervous System Diseases
Mental Disorders
Neuroimaging
Emotions
Thinking

Keywords

  • SYSNEURO

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The Spiritual Brain : Selective Cortical Lesions Modulate Human Self-Transcendence. / Urgesi, Cosimo; Aglioti, Salvatore M.; Skrap, Miran; Fabbro, Franco.

In: Neuron, Vol. 65, No. 3, 11.02.2010, p. 309-319.

Research output: Contribution to journalArticle

Urgesi, Cosimo ; Aglioti, Salvatore M. ; Skrap, Miran ; Fabbro, Franco. / The Spiritual Brain : Selective Cortical Lesions Modulate Human Self-Transcendence. In: Neuron. 2010 ; Vol. 65, No. 3. pp. 309-319.
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