Abstract
Syndrome X is the term applied to patients with anginal-type chest pain who, despite a positive exercise stress test, have angiographically normal coronary arteries. Such patients probably belong to a heterogeneous group, and in a proportion the exercise test is falsely positive. With the availability of more accurate techniques for the detection of myocardial ischaemia, it is apparent that some patients can be shown to develop transient myocardial ischaemia with stress. The paradox of normal coronary arteries and a positive exercise test may be resolved by improved understanding of the regulatory control of regional myocardial blood flow, particularly at the level of the microvasculature, and of the metabolic expression of myocardial ischaemia.
| Original language | English |
|---|---|
| Pages (from-to) | 293-301 |
| Number of pages | 9 |
| Journal | International Journal of Cardiology |
| Volume | 35 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1992 |
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Keywords
- Microvascular angina
- Myocardial ischemia
- Syndrome X
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
The ST segment - the herald of ischaemia, the siren of misdiagnosis, or syndrome X? / Holdright, Diana R.; Rosano, Giuseppe M C; Sarrel, Philip M.; Poole-Wilson, Philip A.
In: International Journal of Cardiology, Vol. 35, No. 3, 1992, p. 293-301.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The ST segment - the herald of ischaemia, the siren of misdiagnosis, or syndrome X?
AU - Holdright, Diana R.
AU - Rosano, Giuseppe M C
AU - Sarrel, Philip M.
AU - Poole-Wilson, Philip A.
PY - 1992
Y1 - 1992
N2 - Syndrome X is the term applied to patients with anginal-type chest pain who, despite a positive exercise stress test, have angiographically normal coronary arteries. Such patients probably belong to a heterogeneous group, and in a proportion the exercise test is falsely positive. With the availability of more accurate techniques for the detection of myocardial ischaemia, it is apparent that some patients can be shown to develop transient myocardial ischaemia with stress. The paradox of normal coronary arteries and a positive exercise test may be resolved by improved understanding of the regulatory control of regional myocardial blood flow, particularly at the level of the microvasculature, and of the metabolic expression of myocardial ischaemia.
AB - Syndrome X is the term applied to patients with anginal-type chest pain who, despite a positive exercise stress test, have angiographically normal coronary arteries. Such patients probably belong to a heterogeneous group, and in a proportion the exercise test is falsely positive. With the availability of more accurate techniques for the detection of myocardial ischaemia, it is apparent that some patients can be shown to develop transient myocardial ischaemia with stress. The paradox of normal coronary arteries and a positive exercise test may be resolved by improved understanding of the regulatory control of regional myocardial blood flow, particularly at the level of the microvasculature, and of the metabolic expression of myocardial ischaemia.
KW - Microvascular angina
KW - Myocardial ischemia
KW - Syndrome X
UR - http://www.scopus.com/inward/record.url?scp=0026653515&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026653515&partnerID=8YFLogxK
U2 - 10.1016/0167-5273(92)90226-S
DO - 10.1016/0167-5273(92)90226-S
M3 - Article
C2 - 1612791
AN - SCOPUS:0026653515
VL - 35
SP - 293
EP - 301
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
IS - 3
ER -