The strain of mouse and assay conditions influence whether MuIFN-γ primes or activates macrophages for tumor cell killing

J. L. Pace, L. Varesio, S. W. Russell, E. Blasi

Research output: Contribution to journalArticlepeer-review

Abstract

Investigators from two different laboratories have compared several variables in the short-term macrophage-mediated cytotoxicity assays used by each group to study the role of MuIFN-γ in macrophage activation. The findings suggest that the capacity of MuIFN-γ to activate macrophages without the need for a second triggering stimulus is related to assay conditions and, most especially, the strain of mouse used to provide the macrophages.

Original languageEnglish
Pages (from-to)475-479
Number of pages5
JournalJournal of Leukocyte Biology
Volume37
Issue number4
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Cell Biology

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