The strain of mouse and assay conditions influence whether MuIFN-γ primes or activates macrophages for tumor cell killing

J. L. Pace, L. Varesio, S. W. Russell, E. Blasi

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Investigators from two different laboratories have compared several variables in the short-term macrophage-mediated cytotoxicity assays used by each group to study the role of MuIFN-γ in macrophage activation. The findings suggest that the capacity of MuIFN-γ to activate macrophages without the need for a second triggering stimulus is related to assay conditions and, most especially, the strain of mouse used to provide the macrophages.

Original languageEnglish
Pages (from-to)475-479
Number of pages5
JournalJournal of Leukocyte Biology
Volume37
Issue number4
Publication statusPublished - 1985

Fingerprint

Macrophages
Neoplasms
Macrophage Activation
Research Personnel

ASJC Scopus subject areas

  • Cell Biology

Cite this

The strain of mouse and assay conditions influence whether MuIFN-γ primes or activates macrophages for tumor cell killing. / Pace, J. L.; Varesio, L.; Russell, S. W.; Blasi, E.

In: Journal of Leukocyte Biology, Vol. 37, No. 4, 1985, p. 475-479.

Research output: Contribution to journalArticle

@article{85f6456f7e3c41e1a783bc3d1bf0efa7,
title = "The strain of mouse and assay conditions influence whether MuIFN-γ primes or activates macrophages for tumor cell killing",
abstract = "Investigators from two different laboratories have compared several variables in the short-term macrophage-mediated cytotoxicity assays used by each group to study the role of MuIFN-γ in macrophage activation. The findings suggest that the capacity of MuIFN-γ to activate macrophages without the need for a second triggering stimulus is related to assay conditions and, most especially, the strain of mouse used to provide the macrophages.",
author = "Pace, {J. L.} and L. Varesio and Russell, {S. W.} and E. Blasi",
year = "1985",
language = "English",
volume = "37",
pages = "475--479",
journal = "Journal of Leukocyte Biology",
issn = "0741-5400",
publisher = "FASEB",
number = "4",

}

TY - JOUR

T1 - The strain of mouse and assay conditions influence whether MuIFN-γ primes or activates macrophages for tumor cell killing

AU - Pace, J. L.

AU - Varesio, L.

AU - Russell, S. W.

AU - Blasi, E.

PY - 1985

Y1 - 1985

N2 - Investigators from two different laboratories have compared several variables in the short-term macrophage-mediated cytotoxicity assays used by each group to study the role of MuIFN-γ in macrophage activation. The findings suggest that the capacity of MuIFN-γ to activate macrophages without the need for a second triggering stimulus is related to assay conditions and, most especially, the strain of mouse used to provide the macrophages.

AB - Investigators from two different laboratories have compared several variables in the short-term macrophage-mediated cytotoxicity assays used by each group to study the role of MuIFN-γ in macrophage activation. The findings suggest that the capacity of MuIFN-γ to activate macrophages without the need for a second triggering stimulus is related to assay conditions and, most especially, the strain of mouse used to provide the macrophages.

UR - http://www.scopus.com/inward/record.url?scp=0021957781&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021957781&partnerID=8YFLogxK

M3 - Article

VL - 37

SP - 475

EP - 479

JO - Journal of Leukocyte Biology

JF - Journal of Leukocyte Biology

SN - 0741-5400

IS - 4

ER -