Abstract
Inflammatory monocytes play important functions in antiviral immune responses, including release of inflammatory cytokines and antigen presentation to T lymphocytes. Depending on the pathological context, these functions might translate into beneficial or detrimental effects in the resolution of the disease. Recent literature has highlighted a role for inflammatory monocytes also in direct suppression of B cell responses. In this review, we will briefly discuss research showing the relationship between inflammatory monocytes and B lymphocytes, its functional consequences on antiviral antibody responses, and possible implications in the design of future vaccination strategies.
Original language | English |
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Pages (from-to) | 327-333 |
Number of pages | 7 |
Journal | Viral Immunology |
Volume | 33 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2020 |
Keywords
- B cell
- humoral immunity
- inflammatory monocytes
- nitric oxide
- suppression
ASJC Scopus subject areas
- Immunology
- Molecular Medicine
- Virology