TY - JOUR
T1 - The supraciliary space as a suitable pathway for glaucoma surgery
T2 - Ho-hum or home run?
AU - Figus, Michele
AU - Posarelli, Chiara
AU - Passani, Andrea
AU - Albert, Timothy G.
AU - Oddone, Francesco
AU - Sframeli, Angela Tindara
AU - Nardi, Marco
PY - 2017/11/1
Y1 - 2017/11/1
N2 - The supraciliary space is a physiological route for aqueous humor outflow located anteriorly between the outer surface of the ciliary body and the internal surface of the sclera. Posteriorly, the suprachoroidal space is located between the choroid and the internal surface of the sclera. These spaces have been targeted as suitable and helpful pathways for glaucoma treatment, alternatives to the traditional subconjunctival space. The subconjunctival surgical pathway is affected by several limitations such as poor cosmesis, a lifetime risk for endophthalmitis, and an unpredictable wound healing response. Because of these limitations, the supraciliary space has gained growing interest as a possible target for new glaucoma drainage devices such as: Gold Micro Shunt (SOLX Inc.; Waltham, MA, USA), iStent Supra (Glaukos Corporation, Laguna Hills, CA, USA), CyPass Micro-Stent (Transcend Medical Inc., Menlo Park, CA, USA), Aquashunt (OPKO health Inc., Miami, FL, USA), STARflo (iSTAR Medical, Isnes, Belgium), and Esnoper-Clip implant (AJL Ophthalmics, Álava, Spain). We review the current literature concerning the supraciliary space to evaluate its safety and efficacy as a suitable pathway for glaucoma surgical treatment.
AB - The supraciliary space is a physiological route for aqueous humor outflow located anteriorly between the outer surface of the ciliary body and the internal surface of the sclera. Posteriorly, the suprachoroidal space is located between the choroid and the internal surface of the sclera. These spaces have been targeted as suitable and helpful pathways for glaucoma treatment, alternatives to the traditional subconjunctival space. The subconjunctival surgical pathway is affected by several limitations such as poor cosmesis, a lifetime risk for endophthalmitis, and an unpredictable wound healing response. Because of these limitations, the supraciliary space has gained growing interest as a possible target for new glaucoma drainage devices such as: Gold Micro Shunt (SOLX Inc.; Waltham, MA, USA), iStent Supra (Glaukos Corporation, Laguna Hills, CA, USA), CyPass Micro-Stent (Transcend Medical Inc., Menlo Park, CA, USA), Aquashunt (OPKO health Inc., Miami, FL, USA), STARflo (iSTAR Medical, Isnes, Belgium), and Esnoper-Clip implant (AJL Ophthalmics, Álava, Spain). We review the current literature concerning the supraciliary space to evaluate its safety and efficacy as a suitable pathway for glaucoma surgical treatment.
KW - glaucoma
KW - glaucoma surgery
KW - minimally invasive glaucoma surgery
KW - suprachoroidal space
KW - supraciliary space
UR - http://www.scopus.com/inward/record.url?scp=85026448835&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85026448835&partnerID=8YFLogxK
U2 - 10.1016/j.survophthal.2017.05.002
DO - 10.1016/j.survophthal.2017.05.002
M3 - Review article
C2 - 28506604
AN - SCOPUS:85026448835
VL - 62
SP - 828
EP - 837
JO - Survey of Ophthalmology
JF - Survey of Ophthalmology
SN - 0039-6257
IS - 6
ER -