The surgical patient with Brugada syndrome: A four-case clinical experience

Luisa G. Santambrogio, Simonetta Mencherini, Marinella Fuardo, Flavia Caramella, Antonio Braschi

Research output: Contribution to journalArticlepeer-review


Brugada syndrome is characterized by a distinctive electrocardiographic pattern (right bundle branch block and ST segment elevation in precordial leads) and a high risk of cardiac arrest for malignant dysrhythmia. The genetic basis is a molecular defect of the cardiac sodium channel and the pattern of inheritance is autosomal dominant. Many factors during general anesthesia (medications, bradycardia, temperature changes) could precipitate malignant dysrhythmia in these patients. Because criteria to identify the surgical patient at high risk for developing malignant dysrhythmia are lacking, we can only speculate about the available studies on nonsurgical patients. We describe four patients during general anesthesia and propose intraoperative and postoperative monitoring (the first 36 h).

Original languageEnglish
Pages (from-to)1263-1266
Number of pages4
JournalAnesthesia and Analgesia
Issue number5
Publication statusPublished - May 2005

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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