TY - JOUR
T1 - The synergistic effect of organic acids, phytochemicals and a permeabilizing complex reduces Salmonella Typhimurium 1,4,[5],12:i-shedding in pigs
AU - Ruggeri, Jessica
AU - Foresti, Fabio
AU - Pavesi, Roberta
AU - Terrini, Alessia
AU - Giudici, Francesca
AU - Padoan, Diego
AU - Corradi, Attilio
AU - Ossiprandi, Maria Cristina
AU - Pasquali, Paolo
AU - Alborali, Giovanni Loris
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Salmonella Typhimurium (including S.Typhimurium 1,4,[5],12:i-) and other enteric pathogens cause acute infection in pigs during the weaning stage, often evolving into chronic infections responsible for the introduction of zoonotic bacteria into the slaughterhouse and thus determining carcass contamination. In addition to being zoonotic hazards, these pathogens are responsible for economic losses in affected farms. Traditionally, antibiotic treatments have been largely administered in order to reduce the infection burden but it favored, as a direct consequence, an increase in the number of multi-drug resistance strains. In order to overcome antibiotic-resistance concerns, new alternative control strategies should be developed. In this context, a blend of organic acids, phytochemicals and a permeabilizing complex, administered in feed (Group A - 459 piglets) or water (Group B – 458 piglets), was tested in field conditions for its capability of reducing Salmonella-infection in weaned piglets of an endemic farm. Data recorded were compared to results of a control group (Group C - 456 piglets). Zootechnical parameters were recorded in all animals, while microbiological, serological and PCR analyses were conducted in 15 piglets for each group. Results demonstrated that additive administered in feed improved animal weight gain (better average daily gain [A.D.G.] and increment), and rapidly reduced Salmonella-shedding in feces. Administration of additive in feed gave better results than in water.
AB - Salmonella Typhimurium (including S.Typhimurium 1,4,[5],12:i-) and other enteric pathogens cause acute infection in pigs during the weaning stage, often evolving into chronic infections responsible for the introduction of zoonotic bacteria into the slaughterhouse and thus determining carcass contamination. In addition to being zoonotic hazards, these pathogens are responsible for economic losses in affected farms. Traditionally, antibiotic treatments have been largely administered in order to reduce the infection burden but it favored, as a direct consequence, an increase in the number of multi-drug resistance strains. In order to overcome antibiotic-resistance concerns, new alternative control strategies should be developed. In this context, a blend of organic acids, phytochemicals and a permeabilizing complex, administered in feed (Group A - 459 piglets) or water (Group B – 458 piglets), was tested in field conditions for its capability of reducing Salmonella-infection in weaned piglets of an endemic farm. Data recorded were compared to results of a control group (Group C - 456 piglets). Zootechnical parameters were recorded in all animals, while microbiological, serological and PCR analyses were conducted in 15 piglets for each group. Results demonstrated that additive administered in feed improved animal weight gain (better average daily gain [A.D.G.] and increment), and rapidly reduced Salmonella-shedding in feces. Administration of additive in feed gave better results than in water.
KW - Organic acids
KW - Phytochemicals
KW - Salmonella Typhimurium 1,4,[5],12:i-
KW - Swine
UR - http://www.scopus.com/inward/record.url?scp=85051678851&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85051678851&partnerID=8YFLogxK
U2 - 10.1007/s11259-018-9723-3
DO - 10.1007/s11259-018-9723-3
M3 - Article
C2 - 29790058
AN - SCOPUS:85051678851
VL - 42
SP - 209
EP - 217
JO - Veterinary Research Communications
JF - Veterinary Research Communications
SN - 0165-7380
IS - 3
ER -