Abstract
The aim of this study was to determine the prevalence of trapping-only nodules of the thyroid gland. The study was prospectively performed in patients bearing hot or warm thyroid nodules at pertechnetate scan in the presence of circulating thyrotropin (TSH) within the normal range. The study was restricted to these patients because nodules that suppress TSH are certainly autonomous. In 140 patients showing hot or warm nodules at 30-minute pertechnetate scintigraphy, and normal TSH levels, radioiodine scintigraphy was performed at 24 hours. The trapping-only pattern, i.e., the presence of a cold nodule in late radioiodine scintigraphy was observed in seven patients (5%). Five had benign thyroid nodules, one follicular carcinoma, and one extrathyroid metastases of papillary-follicular carcinoma. Despite controversy on this issue, trapping-only nodules of thyroid should be searched because they have risk of malignancy and must be differentiated from autonomous adenomas at the compensated stage. The search may be limited to patients with normal serum TSH.
| Original language | English |
|---|---|
| Pages (from-to) | 757-762 |
| Number of pages | 6 |
| Journal | Thyroid |
| Volume | 16 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 2006 |
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ASJC Scopus subject areas
- Endocrinology
Cite this
The trapping-only nodules of the thyroid gland : Prevalence study. / Reschini, Eugenio; Ferrari, Carlo; Castellani, Massimo; Matheoud, Roberta; Paracchi, Alessandra; Marotta, Giorgio; Gerundini, Paolo.
In: Thyroid, Vol. 16, No. 8, 08.2006, p. 757-762.Research output: Contribution to journal › Article
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TY - JOUR
T1 - The trapping-only nodules of the thyroid gland
T2 - Prevalence study
AU - Reschini, Eugenio
AU - Ferrari, Carlo
AU - Castellani, Massimo
AU - Matheoud, Roberta
AU - Paracchi, Alessandra
AU - Marotta, Giorgio
AU - Gerundini, Paolo
PY - 2006/8
Y1 - 2006/8
N2 - The aim of this study was to determine the prevalence of trapping-only nodules of the thyroid gland. The study was prospectively performed in patients bearing hot or warm thyroid nodules at pertechnetate scan in the presence of circulating thyrotropin (TSH) within the normal range. The study was restricted to these patients because nodules that suppress TSH are certainly autonomous. In 140 patients showing hot or warm nodules at 30-minute pertechnetate scintigraphy, and normal TSH levels, radioiodine scintigraphy was performed at 24 hours. The trapping-only pattern, i.e., the presence of a cold nodule in late radioiodine scintigraphy was observed in seven patients (5%). Five had benign thyroid nodules, one follicular carcinoma, and one extrathyroid metastases of papillary-follicular carcinoma. Despite controversy on this issue, trapping-only nodules of thyroid should be searched because they have risk of malignancy and must be differentiated from autonomous adenomas at the compensated stage. The search may be limited to patients with normal serum TSH.
AB - The aim of this study was to determine the prevalence of trapping-only nodules of the thyroid gland. The study was prospectively performed in patients bearing hot or warm thyroid nodules at pertechnetate scan in the presence of circulating thyrotropin (TSH) within the normal range. The study was restricted to these patients because nodules that suppress TSH are certainly autonomous. In 140 patients showing hot or warm nodules at 30-minute pertechnetate scintigraphy, and normal TSH levels, radioiodine scintigraphy was performed at 24 hours. The trapping-only pattern, i.e., the presence of a cold nodule in late radioiodine scintigraphy was observed in seven patients (5%). Five had benign thyroid nodules, one follicular carcinoma, and one extrathyroid metastases of papillary-follicular carcinoma. Despite controversy on this issue, trapping-only nodules of thyroid should be searched because they have risk of malignancy and must be differentiated from autonomous adenomas at the compensated stage. The search may be limited to patients with normal serum TSH.
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U2 - 10.1089/thy.2006.16.757
DO - 10.1089/thy.2006.16.757
M3 - Article
VL - 16
SP - 757
EP - 762
JO - Thyroid
JF - Thyroid
SN - 1050-7256
IS - 8
ER -