The administration of baclofen, a GABAb agonist, by direct infusion into the CSF by means of a programmable device, may avoid the undesired side effects of the oral administration of both the same and other antispastic drugs while giving a marked reduction of spasticity. The preliminary results on 12 patients show the total efficacy of this procedure in reducing spasticity markedly.
|Number of pages||6|
|Journal||Journal of Neurosurgical Sciences|
|Publication status||Published - 1993|
ASJC Scopus subject areas
- Clinical Neurology