The tripartite motif family identifies cell compartments

Alexandre Reymond; Germana Meroni; Anna Fantozzi; Giuseppe Merla; Stefano Cairo; Lucilla Luzi; Daniela Riganelli; Elena Zanaria; Silvia Messali; Silvia Cainarca; Alessandro Guffanti; Saverio Minucci; Pier Giuseppe Pelicci; Andrea Ballabio

doi:10.1093/emboj/20.9.2140

The tripartite motif family identifies cell compartments

Alexandre Reymond, Germana Meroni, Anna Fantozzi, Giuseppe Merla, Stefano Cairo, Lucilla Luzi, Daniela Riganelli, Elena Zanaria, Silvia Messali, Silvia Cainarca, Alessandro Guffanti, Saverio Minucci, Pier Giuseppe Pelicci, Andrea Ballabio

Research output: Contribution to journal › Article › peer-review

Abstract

A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a triparite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.

Original language	English
Pages (from-to)	2140-2151
Number of pages	12
Journal	EMBO Journal
Volume	20
Issue number	9
DOIs	https://doi.org/10.1093/emboj/20.9.2140
Publication status	Published - May 1 2001

Keywords

Cell compartmentalization
Functional genomics
Nuclear bodies
RBCC
Tripartite motif

ASJC Scopus subject areas

Genetics
Cell Biology

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10.1093/emboj/20.9.2140

Cite this

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abstract = "A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a triparite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.",

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T1 - The tripartite motif family identifies cell compartments

AU - Reymond, Alexandre

AU - Meroni, Germana

AU - Fantozzi, Anna

AU - Merla, Giuseppe

AU - Cairo, Stefano

AU - Luzi, Lucilla

AU - Riganelli, Daniela

AU - Zanaria, Elena

AU - Messali, Silvia

AU - Cainarca, Silvia

AU - Guffanti, Alessandro

AU - Minucci, Saverio

AU - Pelicci, Pier Giuseppe

AU - Ballabio, Andrea

PY - 2001/5/1

Y1 - 2001/5/1

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AB - A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a triparite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.

KW - Cell compartmentalization

KW - Functional genomics

KW - Nuclear bodies

KW - RBCC

KW - Tripartite motif

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JO - EMBO Journal

JF - EMBO Journal

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The tripartite motif family identifies cell compartments

Abstract

Keywords

ASJC Scopus subject areas

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