Abstract
A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a triparite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.
Original language | English |
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Pages (from-to) | 2140-2151 |
Number of pages | 12 |
Journal | EMBO Journal |
Volume | 20 |
Issue number | 9 |
DOIs | |
Publication status | Published - May 1 2001 |
Keywords
- Cell compartmentalization
- Functional genomics
- Nuclear bodies
- RBCC
- Tripartite motif
ASJC Scopus subject areas
- Genetics
- Cell Biology