The use of a telematic connection for the follow-up of hypertensive patients improves the cardiovascular prognosis

Nicola De Luca, Raffaele Izzo, Guido Iaccarino, Pier Luigi Malini, Carmine Morisco, Francesco Rozza, Gianni Luigi Iovino, Maria Assunta Elena Rao, Clara Bodenizza, Francesca Lanni, Luigi Guerrera, Oreste Arcucci, Bruno Trimarco

Research output: Contribution to journalArticlepeer-review


Background: Inadequate blood pressure (BP) control could be due to incorrect management of hypertensives caused by the lack of interaction between general practitioners (GP) and hypertension specialists. Objectives: To test the effectiveness on BP and total cardiovascular risk (TCVR) control of an internet-based digital network connecting specialists and GPs. Methods: We created a network among the Hypertension Clinic, Federico II University (Naples, Italy), 23 hospital-based hypertension clinics and 60 GPs from the area (CampaniaSalute Network, CS). Randomized GPs enrolled in CS could update online records of patients (n = 1979). As a control, we included 2045 patients referred to the specialist clinics by GPs from outside the network. All patients completed a 2-year follow-up. Results: CS provided a larger reduction in BP [systolic/ diastolic BP (SBP/DBP): 7.3 ± 0.4/5.4 ± 0.3 versus 4.1 ± 0.4/3.1 ± 0.26 mmHg, CS versus control; P<0.001 for both] and percentage of patients with BP <140/ 90 mmHg (CS versus control: baseline, 33 versus 34%, NS; end of follow-up, 51 versus 47%, χ2 = 13.371; P<0.001). A European Society of Hypertension-European Society of Cardiology (ESH/ESC) TCVR score was calculated [from 1 (average) to 5 (very high TCVR)]. The CS group showed a reduction in the mean TCVR score (CS: from 3.5 ± 0.02 to 3.2 ± 0, P <0.01, ANOVA; control group: 3.5 ± 0.03 to 3.4 ± 0.03, NS) and, accordingly, fatal and non-fatal major cardiovascular events (MACE) were less frequent (2.9 versus 4.3%; χ2 = 5.047, P <0.02). CS predicts fewer MACE in multiple binary regression analysis (β:-7.27, P <0.008) reducing the risk for MACE compared to control [odds ratio (OR): 0.838; 95% confidence interval (CI): 0.73-0.96]. Conclusion: Our results support the idea that telemedicine can achieve better control of BP and TCVR.

Original languageEnglish
Pages (from-to)1417-1423
Number of pages7
JournalJournal of Hypertension
Issue number7
Publication statusPublished - Jul 2005


  • Hospitalization
  • Hypertension
  • Telemedicine
  • Therapy

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology


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