The use of antibiotic-impregnated cement in infected reconstructions after resection for bone tumors

M. Mercuri, D. Donati, C. Errani, N. Fabbri, M. De Paolis

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Significant advances in chemotherapy, radiography, and surgical techniques over the past two decades have made limb salvage surgery procedure of choice for most malignant tumours of the extremities. Massive segmental skeletal reconstruction after resection of bone tumours has become increasingly popular [24]. Endoprosthetic replacement and massive bone allograft transplantation following bone tumour resection are common [15]. However, complications are frequent, resulting in reoperation and, at times, even amputation. The relatively high frequency of complications is not unexpected, given the length and nature of the surgical procedures and the high demand placed on the implants [27]. Infection is the major cause of early failure and the most challenging for both surgeon and patient [5, 18, 24]. In literature the infection rate with endoprosthesis or massive bone allograft is between 2.9 and 30% of cases [18, 21].

Original languageEnglish
Title of host publicationInfection and Local Treatment in Orthopedic Surgery
PublisherSpringer Berlin Heidelberg
Pages377-384
Number of pages8
ISBN (Print)9783540479987
DOIs
Publication statusPublished - 2007

ASJC Scopus subject areas

  • Medicine(all)

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    Mercuri, M., Donati, D., Errani, C., Fabbri, N., & De Paolis, M. (2007). The use of antibiotic-impregnated cement in infected reconstructions after resection for bone tumors. In Infection and Local Treatment in Orthopedic Surgery (pp. 377-384). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-47999-4_44