L'IMPIEGO IN TERAPIA DERMATOLOGICA DEGLI ESTRATTI DI AVOGADO E DI SOJA

Translated title of the contribution: The use of avocado and soya extracts in dermatological therapy

L. Valenzano, A. Di Carlo

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

The soap fraction of the vegetable oils of avocado and soya (1/3 avocado oil soap fraction with 2/3 soya oil soap fraction) was tested in scleroderma and in sclerodermiform conditions secondary to other skin diseases. The drug is already in use in France under the commercial name of Piascledine and is particularly rich in stigmaterol (vegetable sterol with precalciferolic activity) and although its action mechanism has not yet been definitively clarified, it would appear to affect the mobilization and utilization of calcium in the tissues. 28 patients were treated with a daily dose of 6 capsules for periods varying from a few months to over a year. Results were fairly satisfactory to the extent that repair time of sclerodermiform dermohypodermitic ulcerations was reduced. Subjectively, the patients noted a reduction of pain and less difficulty in performing movements. The drug was well tolerated; only 5 patients noticed slight signs of gastric intolerance (nausea, anorexia, vomiting) and 1 patient presented pruriginous symptomatology which regressed when the dose was reduced. It is concluded that although the drug does not resolve the etiological problem, it can be usefully employed alone or in association with other treatment, in the therapy of scleroderma and of secondary sclerodermiform states.

Original languageItalian
Title of host publicationGiornale Italiano di Dermatologia / Minerva Dermatologica
Pages212-214
Number of pages3
Volume110
Edition5
Publication statusPublished - 1975

Fingerprint

Persea
Soaps
Pharmaceutical Preparations
Soybean Oil
Plant Oils
Anorexia
Sterols
Therapeutics
Skin Diseases
Vegetables
Nausea
France
Capsules
Names
Vomiting
Stomach
Oils
Calcium
Pain

ASJC Scopus subject areas

  • Dermatology

Cite this

Valenzano, L., & Di Carlo, A. (1975). L'IMPIEGO IN TERAPIA DERMATOLOGICA DEGLI ESTRATTI DI AVOGADO E DI SOJA. In Giornale Italiano di Dermatologia / Minerva Dermatologica (5 ed., Vol. 110, pp. 212-214)

L'IMPIEGO IN TERAPIA DERMATOLOGICA DEGLI ESTRATTI DI AVOGADO E DI SOJA. / Valenzano, L.; Di Carlo, A.

Giornale Italiano di Dermatologia / Minerva Dermatologica. Vol. 110 5. ed. 1975. p. 212-214.

Research output: Chapter in Book/Report/Conference proceedingChapter

Valenzano, L & Di Carlo, A 1975, L'IMPIEGO IN TERAPIA DERMATOLOGICA DEGLI ESTRATTI DI AVOGADO E DI SOJA. in Giornale Italiano di Dermatologia / Minerva Dermatologica. 5 edn, vol. 110, pp. 212-214.
Valenzano L, Di Carlo A. L'IMPIEGO IN TERAPIA DERMATOLOGICA DEGLI ESTRATTI DI AVOGADO E DI SOJA. In Giornale Italiano di Dermatologia / Minerva Dermatologica. 5 ed. Vol. 110. 1975. p. 212-214
Valenzano, L. ; Di Carlo, A. / L'IMPIEGO IN TERAPIA DERMATOLOGICA DEGLI ESTRATTI DI AVOGADO E DI SOJA. Giornale Italiano di Dermatologia / Minerva Dermatologica. Vol. 110 5. ed. 1975. pp. 212-214
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