The use of ciprofloxacin and fluconazole in Italian neonatal intensive care units: A nationwide survey

Chiara Pandolfini, Sequi Marco, Manzoni Paolo, Bonati Maurizio

Research output: Contribution to journalArticle


Background: Treatment and prophylaxis of sepsis in very low birth weight neonates is a matter of concern and research is being undertaken with the aim to give rise to shared approaches based on solid evidence. As part of a European initiative, a survey was set up to describe the use of two drugs in this area. The Italian national practices concerning neonatal sepsis, as well as calls for related guidance, are described.Methods: A standardized and previously tested questionnaire was submitted online to all Italian level III NICUs. A 5-point Likert scale was used to analyze attitudinal replies. Categorical variables were compared by χ2 analysis and 2-tailed P-values are reported.Results: Data was provided by 38 Italian NICUs (36% of the country's level III centers), 53% of which have 1-10 cases of bacterial sepsis monthly and 90% a prevalence of

Original languageEnglish
Article number5
JournalBMC Pediatrics
Issue number1
Publication statusPublished - Jan 7 2013



  • Ciprofloxacin
  • Fluconazole
  • Health care surveys
  • Intensive care units
  • Italy
  • Neonatal
  • Practice guidelines as topic

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this