L'impiego della Tomografia Computerizzata ad alta risoluzione (HRCT) per la diagnosi di rigetto e per il monitoraggio dell'anastomosi sulla via aerea nei pazienti sottoposti a trapianto di polmone. Studio preliminare.

Translated title of the contribution: The use of high resolution computerized tomography (HRCT) for the diagnosis of rejection and for monitoring air-way anastomosis in patients who have undergone lung transplantation. Preliminary study

G. Melloni, P. Zannini, M. Solca, A. Baisi, G. Nastri, A. Vanzulli, A. Del Maschio

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

March, 1991, to June, 1992, five lung transplantations for end-stage lung disease were successfully performed at the Ospedale Maggiore Policlinico in Milan. All patients underwent high-resolution CT (HRCT) of the lung in a complex follow-up program to identify specific abnormalities of acute and chronic rejection (bronchiolitis obliterans) and to monitor the resolution of the bronchial anastomosis. Twenty-two HRCT exams were performed. In patients with acute rejection HRCT failed to identify specific abnormalities of lung parenchyma. In contrast, in one patient with pathological evidence of early bronchiolitis obliterans HRCT showed decreased peripheral vascularization. In the study of the bronchial anastomosis, HRCT showed optimal anastomosis resolution in 4 patients, whereas in one patient with a granuloma demonstrated by fibrobronchoscopy it confirmed the lesion showing also a small pneumomediastinum. Even though the HRCT finding of decreased peripheral vascularization does not appear to be specific for bronchiolitis obliterans, it may be of value in suggesting the diagnosis of early bronchiolitis obliterans in lung transplant. HRCT should be used in all patients with bronchoscopic diagnosis of bronchial complication to study the lesion and its mediastinal spread.

Original languageItalian
Pages (from-to)623-627
Number of pages5
JournalRadiologia Medica
Volume89
Issue number5
Publication statusPublished - May 1995

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Lung Transplantation
Bronchiolitis Obliterans
Air
Tomography
Lung
Mediastinal Emphysema
Granuloma
Lung Diseases
Transplants

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

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title = "L'impiego della Tomografia Computerizzata ad alta risoluzione (HRCT) per la diagnosi di rigetto e per il monitoraggio dell'anastomosi sulla via aerea nei pazienti sottoposti a trapianto di polmone. Studio preliminare.",
abstract = "March, 1991, to June, 1992, five lung transplantations for end-stage lung disease were successfully performed at the Ospedale Maggiore Policlinico in Milan. All patients underwent high-resolution CT (HRCT) of the lung in a complex follow-up program to identify specific abnormalities of acute and chronic rejection (bronchiolitis obliterans) and to monitor the resolution of the bronchial anastomosis. Twenty-two HRCT exams were performed. In patients with acute rejection HRCT failed to identify specific abnormalities of lung parenchyma. In contrast, in one patient with pathological evidence of early bronchiolitis obliterans HRCT showed decreased peripheral vascularization. In the study of the bronchial anastomosis, HRCT showed optimal anastomosis resolution in 4 patients, whereas in one patient with a granuloma demonstrated by fibrobronchoscopy it confirmed the lesion showing also a small pneumomediastinum. Even though the HRCT finding of decreased peripheral vascularization does not appear to be specific for bronchiolitis obliterans, it may be of value in suggesting the diagnosis of early bronchiolitis obliterans in lung transplant. HRCT should be used in all patients with bronchoscopic diagnosis of bronchial complication to study the lesion and its mediastinal spread.",
author = "G. Melloni and P. Zannini and M. Solca and A. Baisi and G. Nastri and A. Vanzulli and {Del Maschio}, A.",
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AU - Zannini, P.

AU - Solca, M.

AU - Baisi, A.

AU - Nastri, G.

AU - Vanzulli, A.

AU - Del Maschio, A.

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