Abstract
Paget's disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain. Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this disorder.
Original language | English |
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Pages (from-to) | 1052-1063 |
Number of pages | 12 |
Journal | Mini-Reviews in Medicinal Chemistry |
Volume | 9 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2009 |
Keywords
- Bisphosphonates
- Bone turnover
- Neridronate
- Paget's disease of bone
- Pamidronate
- Zoledronic acid
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery