The use of intravenous aminobisphosphonates for the treatment of Paget's disease of bone

Luigi Gennari, Daniela Merlotti, Giuseppe Mossetti, Domenico Rendina, Vincenzo De Paola, Giuseppe Martini, Ranuccio Nuti

Research output: Contribution to journalArticlepeer-review

Abstract

Paget's disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain. Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this disorder.

Original languageEnglish
Pages (from-to)1052-1063
Number of pages12
JournalMini-Reviews in Medicinal Chemistry
Volume9
Issue number9
DOIs
Publication statusPublished - 2009

Keywords

  • Bisphosphonates
  • Bone turnover
  • Neridronate
  • Paget's disease of bone
  • Pamidronate
  • Zoledronic acid

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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