The use of LHRH agonists and antagonists in the treatment of myomata

P. Vercellini, B. Zaina, L. Trespidi, G. Stellato, S. Vicentini, A. Pisacreta

Research output: Contribution to journalArticlepeer-review


In women with fibriods, luteinizing hormone-releasing hormone (LHRH) agonists help to correct menorrhagia-associated anemia, reducing the need for blood transfusions and emergency surgery. Long-term treatments with add-back therapies are feasible but should be limited to selected patients. Gonadotropin-releasing hormone agonists may facilitate hysteroscopic myomectomy especially in the presence of intramural tumors. Only preliminary data are available on LHRH antagonists used alone or in combination with surgery, and the practical relevance of avoidance of the flare-up phase in women with fibroids remains to be determined.

Original languageEnglish
Pages (from-to)195-214
Number of pages20
JournalInfertility and Reproductive Medicine Clinics of North America
Issue number1
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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