Abstract
Purpose: The objective was to define the trends of PN use over time at six tertiary care European centers. Methods: Data were retrieved from institutional databases for patients treated with either PN or radical nephrectomy (RN) for stages T1-2N0M0 renal cell carcinoma (RCC) between 1987 and 2007. For purpose of temporal trend analyses patients were divided into five equally sized groups according to the date of surgery. Categorical and multivariable logistic regression analyses assessed predictors of PN use. Results: Overall 597 (31.7%) patients were treated with PN. Overall, a 4.5-fold increase of PN was recorded. The absolute increases were 41.7-86.3%, 14.9-69.3% and 8.1-35.3% for lesions ≤2 cm, 2.1-4 cm and 4.1-7 cm (chi-square trend test p <0.001), respectively. In multivariable logistic regression models, decreasing tumor size, younger age, more contemporary date of surgery, male gender and institutional PN rate represented independent predictors of the individual probability of treatment with PN. Lack of data from community hospitals limits the generalizability of our findings. Conclusion: Based on data from six tertiary care centers, the contemporary rate of PN ranges from 86 to 35% for renal masses ≤2 cm to 4.1-7 cm and is indicative of excellent quality of care.
| Original language | English |
|---|---|
| Pages (from-to) | 636-642 |
| Number of pages | 7 |
| Journal | European Journal of Surgical Oncology |
| Volume | 35 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2009 |
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Keywords
- Kidney neoplasms
- Partial nephrectomy
- Renal cell carcinoma
- Temporal trends
ASJC Scopus subject areas
- Oncology
- Surgery
Cite this
The use of partial nephrectomy in European tertiary care centers. / Zini, L.; Patard, J. J.; Capitanio, U.; Mejean, A.; Villers, A.; de La Taille, A.; Ficarra, V.; Crepel, M.; Bertini, R.; Salomon, L.; Verhoest, G.; Perrotte, P.; Bensalah, K.; Arjane, P.; Biserte, J.; Montorsi, F.; Karakiewicz, P.
In: European Journal of Surgical Oncology, Vol. 35, No. 6, 06.2009, p. 636-642.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The use of partial nephrectomy in European tertiary care centers
AU - Zini, L.
AU - Patard, J. J.
AU - Capitanio, U.
AU - Mejean, A.
AU - Villers, A.
AU - de La Taille, A.
AU - Ficarra, V.
AU - Crepel, M.
AU - Bertini, R.
AU - Salomon, L.
AU - Verhoest, G.
AU - Perrotte, P.
AU - Bensalah, K.
AU - Arjane, P.
AU - Biserte, J.
AU - Montorsi, F.
AU - Karakiewicz, P.
PY - 2009/6
Y1 - 2009/6
N2 - Purpose: The objective was to define the trends of PN use over time at six tertiary care European centers. Methods: Data were retrieved from institutional databases for patients treated with either PN or radical nephrectomy (RN) for stages T1-2N0M0 renal cell carcinoma (RCC) between 1987 and 2007. For purpose of temporal trend analyses patients were divided into five equally sized groups according to the date of surgery. Categorical and multivariable logistic regression analyses assessed predictors of PN use. Results: Overall 597 (31.7%) patients were treated with PN. Overall, a 4.5-fold increase of PN was recorded. The absolute increases were 41.7-86.3%, 14.9-69.3% and 8.1-35.3% for lesions ≤2 cm, 2.1-4 cm and 4.1-7 cm (chi-square trend test p <0.001), respectively. In multivariable logistic regression models, decreasing tumor size, younger age, more contemporary date of surgery, male gender and institutional PN rate represented independent predictors of the individual probability of treatment with PN. Lack of data from community hospitals limits the generalizability of our findings. Conclusion: Based on data from six tertiary care centers, the contemporary rate of PN ranges from 86 to 35% for renal masses ≤2 cm to 4.1-7 cm and is indicative of excellent quality of care.
AB - Purpose: The objective was to define the trends of PN use over time at six tertiary care European centers. Methods: Data were retrieved from institutional databases for patients treated with either PN or radical nephrectomy (RN) for stages T1-2N0M0 renal cell carcinoma (RCC) between 1987 and 2007. For purpose of temporal trend analyses patients were divided into five equally sized groups according to the date of surgery. Categorical and multivariable logistic regression analyses assessed predictors of PN use. Results: Overall 597 (31.7%) patients were treated with PN. Overall, a 4.5-fold increase of PN was recorded. The absolute increases were 41.7-86.3%, 14.9-69.3% and 8.1-35.3% for lesions ≤2 cm, 2.1-4 cm and 4.1-7 cm (chi-square trend test p <0.001), respectively. In multivariable logistic regression models, decreasing tumor size, younger age, more contemporary date of surgery, male gender and institutional PN rate represented independent predictors of the individual probability of treatment with PN. Lack of data from community hospitals limits the generalizability of our findings. Conclusion: Based on data from six tertiary care centers, the contemporary rate of PN ranges from 86 to 35% for renal masses ≤2 cm to 4.1-7 cm and is indicative of excellent quality of care.
KW - Kidney neoplasms
KW - Partial nephrectomy
KW - Renal cell carcinoma
KW - Temporal trends
UR - http://www.scopus.com/inward/record.url?scp=67349152697&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67349152697&partnerID=8YFLogxK
U2 - 10.1016/j.ejso.2008.07.008
DO - 10.1016/j.ejso.2008.07.008
M3 - Article
VL - 35
SP - 636
EP - 642
JO - European Journal of Surgical Oncology
JF - European Journal of Surgical Oncology
SN - 0748-7983
IS - 6
ER -