Since its first presentation ranitidine seemed to be very useful in Paediatric Surgery. We used it in a lot of different conditions: gastroesophageal reflux (GER), gastritis and peptic ulcer, prevention of stress ulcer. In the last seven years, we had no troubles related with the administration of ranitidne during the hospitalization because of the intravenous preparation or because the confection of the exact dose to be administered by mouth by internal pharmacy. Some troubles were reported by parents because the impossibility to give the exact amount at the dose of 4 mg/kg/day in a little infant. In the last five months we had the opportunity to treat 10 patients (4 with pure GER, 3 with GER after long-gap anastomosis of the esophagus, 1 with tracheo-esophageal fistula, 1 with hiatal hernia, 1 with ingestion of caustic soda) with a new persentation in syrup at the dose of 10 mg/kg/day. After two months we had a complete recovery in the cases with pure GER, and an important improvement in all the other cases. No troubles were reported by parents especially related with the accuracy of the dose. Results were evaluated by 24 h ph-monitoring and by endoscopy with biopsies.
|Translated title of the contribution||The use of ranitidine syrup in pediatric surgery|
|Number of pages||9|
|Journal||Rassegna Italiana di Chirurgia Pediatrica|
|Publication status||Published - 1990|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health