The use of TachoSil for the prevention of postoperative complications after groin dissection in cases of gynecologic malignancy

Alessandro Buda, Robert Fruscio, Cecilia Pirovano, Mauro Signorelli, Marta Betti, Rodolfo Milani

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective: To evaluate the effect of TachoSil in preventing postoperative complications after groin dissection performed for primary or recurrent gynecologic malignancy. Methods: In a case-control analysis, the incidence of postoperative complications - including lymphocyst formation, wound breakdown and/or infection, and chronic lymphedema - was examined among 8 patients who received TachoSil and 16 controls (standard technique) treated for vulvar cancer or recurrent ovarian/breast cancer at San Gerardo Hospital, Monza, Italy, from 2008 to 2011. Results: Thirty-eight inguinal dissections were performed in the 24 patients. Bilateral groin dissection was performed in 14 patients (n = 4 in the study group; n = 10 in the control group). Patients in the study group had a lower mean daily drainage volume than those in the control group (133 mL [range, 50-356 mL] vs 320 mL [range, 67-472 mL]; P <0.001) and a lower incidence of lymphocyst requiring drainage (25.0% vs 62.5%), cellulitis (12.0% vs 25.0%), and wound infection (0.0% vs 25.0%). Conclusion: The use of TachoSil seems to be effective in reducing the rate of postoperative complications after inguinofemoral lymphadenectomy in cases of gynecologic malignancy.

Original languageEnglish
Pages (from-to)217-219
Number of pages3
JournalInternational Journal of Gynecology and Obstetrics
Volume117
Issue number3
DOIs
Publication statusPublished - Jun 2012

Fingerprint

Groin
Dissection
Drainage
Neoplasms
Vulvar Neoplasms
Control Groups
Cellulitis
Lymphedema
Incidence
Wound Infection
Lymph Node Excision
Ovarian Neoplasms
Italy
Breast Neoplasms
TachoSil
Wounds and Injuries
Infection

Keywords

  • Gynecologic malignancy
  • Inguinofemoral groin dissection
  • Postoperative complications
  • Surgical patch

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

The use of TachoSil for the prevention of postoperative complications after groin dissection in cases of gynecologic malignancy. / Buda, Alessandro; Fruscio, Robert; Pirovano, Cecilia; Signorelli, Mauro; Betti, Marta; Milani, Rodolfo.

In: International Journal of Gynecology and Obstetrics, Vol. 117, No. 3, 06.2012, p. 217-219.

Research output: Contribution to journalArticle

Buda, Alessandro ; Fruscio, Robert ; Pirovano, Cecilia ; Signorelli, Mauro ; Betti, Marta ; Milani, Rodolfo. / The use of TachoSil for the prevention of postoperative complications after groin dissection in cases of gynecologic malignancy. In: International Journal of Gynecology and Obstetrics. 2012 ; Vol. 117, No. 3. pp. 217-219.
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