The use of ultrasound to assess giant cell arteritis: Review of the current evidence and practical guide for the rheumatologist

Sara Monti, Alberto Floris, Cristina Ponte, Wolfgang A. Schmidt, Andreas P. Diamantopoulos, Claudio Pereira, Jennifer Piper, Raashid Luqmani

Research output: Contribution to journalReview article

Abstract

Colour duplex sonography (CDS) of temporal arteries and large vessels is an emerging diagnostic tool for GCA. CDS can detect wall oedema, known as a halo, throughout the length of the vessel and shows higher sensitivity compared with biopsy. Specificity reaches 100% in case of bilateral halos. A positive compression sign has been demonstrated to be a robust marker with excellent inter-observer agreement. The assessment of other large vessels, particularly the axillary arteries, is recognized to further increase the sensitivity and to reliably represent extra-cranial involvement in other areas. Nevertheless, CDS use is still not widespread in routine clinical practice and requires skilled sonographers. Moreover, its role in the follow-up of patients still needs to be defined. The aim of this review is to provide the current evidence and technical parameters to support the rheumatologist in the CDS evaluation of patients with suspected GCA.

Original languageEnglish
Article numberkex173
Pages (from-to)227-235
Number of pages9
JournalRheumatology (United Kingdom)
Volume57
Issue number2
DOIs
Publication statusPublished - Feb 1 2018
Externally publishedYes

Keywords

  • Colour duplex sonography
  • Giant cell arteritis
  • Large vessel vasculitis
  • Ultrasound

ASJC Scopus subject areas

  • Rheumatology
  • Pharmacology (medical)

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  • Cite this

    Monti, S., Floris, A., Ponte, C., Schmidt, W. A., Diamantopoulos, A. P., Pereira, C., Piper, J., & Luqmani, R. (2018). The use of ultrasound to assess giant cell arteritis: Review of the current evidence and practical guide for the rheumatologist. Rheumatology (United Kingdom), 57(2), 227-235. [kex173]. https://doi.org/10.1093/rheu