TY - JOUR
T1 - The value of glycosylated haemoglobin measurements in monitoring diabetic out-patients and correlation with various clinical parameters
AU - Melino, G.
PY - 1988
Y1 - 1988
N2 - 448 diabetic out-patients, type I and type II, were followed for 24 months to assess the monitoring efficacy of HbA1. In 349 patients HbA1 was statistically correlated to fasting plasma glucose, clinical-metabolic control, therapy, self-monitoring, age, sex, weight, body mass and surface index. However the latter five parameters lost their statistical significance in a multivariate analysis. Sequential HbA1 and fasting plasma glucose measurements in the same patient showed a variable correlation to the metabolic control, depending on the type of patient. HbA1 had a better relationship to the metabolic control than fasting plasma glucose only in new-diabetics and in unstable badly controlled insulin-dependent patients. In conclusion, the best use of HbA1 is in such patients, provided that the result is available at the clinic.
AB - 448 diabetic out-patients, type I and type II, were followed for 24 months to assess the monitoring efficacy of HbA1. In 349 patients HbA1 was statistically correlated to fasting plasma glucose, clinical-metabolic control, therapy, self-monitoring, age, sex, weight, body mass and surface index. However the latter five parameters lost their statistical significance in a multivariate analysis. Sequential HbA1 and fasting plasma glucose measurements in the same patient showed a variable correlation to the metabolic control, depending on the type of patient. HbA1 had a better relationship to the metabolic control than fasting plasma glucose only in new-diabetics and in unstable badly controlled insulin-dependent patients. In conclusion, the best use of HbA1 is in such patients, provided that the result is available at the clinic.
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M3 - Article
AN - SCOPUS:0024244704
VL - 1
SP - 77
EP - 87
JO - Clinical Chemistry and Enzymology Communications
JF - Clinical Chemistry and Enzymology Communications
SN - 0892-2187
IS - 2
ER -